ReviewHuman genetics2011
Biobanking residual tissues.
Review in Human genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Recommendations for the return of research results to study participants and guardians: a report from the Children's Oncology Group.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2012Guideline
- The European Health Data Space and biobanking in Europe: synergies, tensions and the future governance of data-driven health research.Frontiers in genetics · 2026Review
- From 'Consent or Anonymise' to 'Share and Protect': Facilitating Access to Surplus Tissue for Research Whilst Safeguarding Donor Interests.Health care analysis : HCA : journal of health philosophy and policy · 2021Article
- Prediction and clinical utility of a contralateral breast cancer risk model.Breast cancer research : BCR · 2019Article
- Cryo-Gel embedding compound for renal biopsy biobanking.Scientific reports · 2019Article
- Biobank Quality Management in the BBMRI.be Network.Frontiers in medicine · 2019Article
- Broad consent for health care-embedded biobanking: understanding and reasons to donate in a large patient sample.Genetics in medicine : official journal of the American College of Medical Genetics · 2018Article
- Brain tumor biobanking in the precision medicine era: building a high-quality resource for translational research in neuro-oncology.Neuro-oncology practice · 2017Review
- Epitope recognition in the human-pig comparison model on fixed and embedded material.The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society · 2015Article
- An effective multisource informed consent procedure for research and clinical practice: an observational study of patient understanding and awareness of their roles as research stakeholders in a cancer biobank.BMC medical ethics · 2013Observational
- Analysis of human tissue management models for medical research: preparation for implementation of the 2012 revision of the Bioethics and Safety Act of Korea.Journal of Korean medical science · 2013Article
- Biobanking for research in surgery: are surgeons in charge for advancing translational research or mere assistants in biomaterial and data preservation?Langenbeck's archives of surgery · 2013Review
- Applying ecological and evolutionary theory to cancer: a long and winding road.Evolutionary applications · 2013Article
- Structural requirements of research tissue banks derived from standardized project surveillance.Virchows Archiv : an international journal of pathology · 2012Article
- Reflexive research ethics in fetal tissue xenotransplantation research.Accountability in research · 2012Article
- The art and science of biobanking.Human genetics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Health-care research relies largely on human materials stored in highly specialised biorepositories. Medical translational research on tissues can be performed using a variety of resources in distinct situations. The best known is the secondary use of pathology archives where paraffin-embedded tissues are stored for diagnostic reasons. Another is collecting and storing frozen material obtained from leftover surgical diagnosis. Such residual tissues can either be used directly in research projects or used in the context of a clinical trial with new interventional medicinal products. The latter can make the regulations governing the use of these materials for medical research much more complicated. The use of residual materials is very distinct from biobanking projects for which tissue is specifically collected. This article describes the consequences of using residual human material from different sources in distinct situations and why signed informed consent is not always the preferred choice of individual countries regarding the use of residual material. In addition, signed informed consent is overdone when using residual tissues in medical research. We maintain that the opt-out system is a balanced choice if certain requirements are met, relating to sufficient transparency about using residual tissue for research, the purpose of such research and to the confidentiality of the data used in that research. Finally, the international exchange of samples can be based on the laws and regulations of the countries of origin. Respecting these form the basis of what can and cannot be done in the country where the research on the samples is being performed.
Indexed as
Identifiers
21814798What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.