ArticleThe American journal of tropical medicine and hygiene2011
Urine antibiotic activity in patients presenting to hospitals in Laos: implications for worsening antibiotic resistance.
Article in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 35 citations in OpenAlex.
- A new point-of-care test for the rapid antimicrobial susceptibility assessment of uropathogens.PloS one · 2023Trial
- Urine bioassay optimisation to assess the association between antimicrobial exposure, pneumococcal carriage and antimicrobial resistance among hospitalised children in Malawi.BMC infectious diseases · 2025Article
- The impact of C-reactive protein testing on treatment-seeking behavior and patients' attitudes toward their care in Myanmar and Thailand.Healthcare in low-resource settings · 2023Article
- Evaluation strategies for measuring pneumococcal conjugate vaccine impact in low-resource settings.Expert review of vaccines · 2022Article
- A random survey of the prevalence of falsified and substandard antibiotics in the Lao PDR.The Journal of antimicrobial chemotherapy · 2022Article
- Antimicrobial use and resistance data in human and animal sectors in the Lao PDR: evidence to inform policy.BMJ global health · 2021Article
- Bacteria and viruses in the upper respiratory tract of Congolese children with radiologically confirmed pneumonia.BMC infectious diseases · 2021Article
- Molecular Detection of Pathogens in Negative Blood Cultures in the Lao People's Democratic Republic.The American journal of tropical medicine and hygiene · 2021Article
- The spread of chloramphenicol-resistant Neisseria meningitidis in Southeast Asia.International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases · 2020Article
- Typhoid in Laos: An 18-Year Perspective.The American journal of tropical medicine and hygiene · 2020Article
- Evaluation of the Active Melioidosis Detect™ test as a point-of-care tool for the early diagnosis of melioidosis: a comparison with culture in Laos.Transactions of the Royal Society of Tropical Medicine and Hygiene · 2019Article
- Defining System Requirements for Simplified Blood Culture to Enable Widespread Use in Resource-Limited Settings.Diagnostics (Basel, Switzerland) · 2019Article
- Factors associated with pneumococcal carriage and density in infants and young children in Laos PDR.PloS one · 2019Article
- A cross-sectional study on the prevalence of antibiotic use prior to laboratory tests at two Ghanaian hospitals.PloS one · 2019Article
- High Rates of Enteric Fever Diagnosis and Lower Burden of Culture-Confirmed Disease in Peri-urban and Rural Nepal.The Journal of infectious diseases · 2018Article
- A comparison of two molecular methods for diagnosing leptospirosis from three different sample types in patients presenting with fever in Laos.Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases · 2018Article
- Frequent Community Use of Antibiotics among a Low-Economic Status Population in Manila, the Philippines: A Prospective Assessment Using a Urine Antibiotic Bioassay.The American journal of tropical medicine and hygiene · 2018Article
- Clostridium difficile infection in the Lao People's Democratic Republic: first isolation and review of the literature.BMC infectious diseases · 2017Review
- Early results for active infective endocarditis.The Pan African medical journal · 2017Article
- Prevalence and predictors of prior antibacterial use among patients presenting to hospitals in Northern Uganda.BMC pharmacology & toxicology · 2015Article
Corrections and comments
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Authors and funding
11 authors at 1 institution in 2 countries.
Funding
Abstract
Widespread use of antibiotics may be important in the spread of antimicrobial resistance. We estimated the proportion of Lao in- and outpatients who had taken antibiotics before medical consultation by detecting antibiotic activity in their urine added to lawns of Bacillus stearothermophilus, Escherichia coli, and Streptococcus pyogenes. In the retrospective (N = 2,058) and prospective studies (N = 1,153), 49.7% (95% confidence interval [CI] = 47.4-52.0) and 36.2% (95% CI = 33.4-38.9), respectively, of Vientiane patients had urinary antibiotic activity detected. The highest frequency of estimated antibiotic pre-treatment was found in patients recruited with suspected central nervous system infections and community-acquired septicemia (both 56.8%). In Vientiane, children had a higher frequency of estimated antibiotic pre-treatment than adults (60.0% versus 46.5%; P < 0.001). Antibiotic use based on patients histories was significantly less frequent than when estimated from urinary antibiotic activity (P < 0.0001).
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Registered trials
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