Trial reportThe American journal of tropical medicine and hygiene2011
Adverse events after mass azithromycin treatments for trachoma in Ethiopia.
Trial report in The American journal of tropical medicine and hygiene, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety of azithromycin in pediatrics: a systematic review and meta-analysis.European journal of clinical pharmacology · 2020Pooled it
- Malaria positivity following a single oral dose of azithromycin among children in Burkina Faso: a randomized controlled trial.BMC infectious diseases · 2022Trial
- Linear growth in preschool children treated with mass azithromycin distributions for trachoma: A cluster-randomized trial.PLoS neglected tropical diseases · 2019Trial
- Does mass azithromycin distribution impact child growth and nutrition in Niger? A cluster-randomized trial.PLoS neglected tropical diseases · 2014Trial
- A cluster randomized study of the safety of integrated treatment of trachoma and lymphatic filariasis in children and adults in Sikasso, Mali.PLoS neglected tropical diseases · 2013Trial
- A cluster-randomized controlled trial evaluating the effects of mass azithromycin treatment on growth and nutrition in Niger.The American journal of tropical medicine and hygiene · 2013Trial
- Cost and community acceptability of enhanced antibiotic distribution approaches for trachoma in the Republic of South Sudan: enhancing the A in SAFE (ETAS) study protocol.BMC ophthalmology · 2023Article
- Trachoma.Nature reviews. Disease primers · 2022Review
- Azithromycin Reduction to Reach Elimination of Trachoma (ARRET): study protocol for a cluster randomized trial of stopping mass azithromycin distribution for trachoma.BMC ophthalmology · 2021Article
- Article
- Coverage assessment survey following trachoma mass drug administration (MDA) in six districts of Oromia, Western Ethiopia, 2017.PLoS neglected tropical diseases · 2019Article
- Self-Reported Side Effects following Mass Administration of Azithromycin to Eliminate Trachoma in Amhara, Ethiopia: Results from a Region-Wide Population-Based Survey.The American journal of tropical medicine and hygiene · 2019Article
- Ocular Chlamydia trachomatis infection: elimination with mass drug administration.Expert review of anti-infective therapy · 2019Review
- Coverage of azithromycin mass treatment for trachoma elimination in Northwestern Ethiopia: a community based cross-sectional study.BMC ophthalmology · 2018Article
- Trachoma: an update on prevention, diagnosis, and treatment.Current opinion in ophthalmology · 2012Review
Corrections and comments
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Authors and funding
10 authors.
Funding
Abstract
During a cluster-randomized clinical trial for trachoma in Ethiopia, two rounds of adverse event surveillance were performed in a random sample of communities after community-wide mass azithromycin treatment. The prevalence of any reported adverse event ranged from 4.9% to 7.0% in children 1-9 years of age and from 17.0% to 18.7% in persons ≥ 10 years of age. Adverse events appeared to cluster by household and perhaps by village. Mass azithromycin distributions were well tolerated in this setting.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.