ArticleJournal of experimental botany2011
The barley amo1 locus is tightly linked to the starch synthase IIIa gene and negatively regulates expression of granule-bound starch synthetic genes.
Article in Journal of experimental botany, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
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Who cites it
22 citing papers in PubMed.
- Regulatory factors of starch metabolism in cereal endosperm.Plant molecular biology · 2026Review
- Food as Medicine: Curbing Type-2 Diabetes Prevalence Through Consumption of High Amylose Starchy Foods in Sub-Saharan Africa.Advanced pharmaceutical bulletin · 2025Review
- Engineering High-Amylose and High-Dietary-Fibre Barley Grains Through Multiplex Genome Editing of Four Starch-Synthetic Genes.Foods (Basel, Switzerland) · 2025Article
- Breeding of Fukumi Fiber, a new six-rowed waxy hull-less barley cultivar containing high levels of β-glucan with a proanthocyanidin-free gene.Breeding science · 2025Article
- Development of a KASP marker set for high-throughput genotyping in Japanese barley breeding programs with various end-use purposes.Breeding science · 2025Article
- QTL Analysis of β-Glucan Content and Other Grain Traits in a Recombinant Population of Spring Barley.International journal of molecular sciences · 2024Article
- Identification of candidate gene for the defective kernel phenotype using bulked segregant RNA and exome capture sequencing methods in wheat.Frontiers in plant science · 2023Article
- Loss of starch synthase IIIa changes starch molecular structure and granule morphology in grains of hexaploid bread wheat.Scientific reports · 2022Article
- Association analysis, genetic diversity and population structure of barley (Hordeum vulgare L.) under heat stress conditions using SSR and ISSR markers linked to primary and secondary metabolites.Molecular biology reports · 2021Article
- Down-Regulation ofFoods (Basel, Switzerland) · 2021Article
- An introductory review of resistant starch type 2 from high-amylose cereal grains and its effect on glucose and insulin homeostasis.Nutrition reviews · 2019Review
- Upregulated Lipid Biosynthesis at the Expense of Starch Production in Potato (Frontiers in plant science · 2019Article
- Rice Mutants Lacking Starch Synthase I or Branching Enzyme IIb Activity Altered Starch Biosynthetic Protein Complexes.Frontiers in plant science · 2018Article
- Formation of starch in plant cells.Cellular and molecular life sciences : CMLS · 2016Review
- The different effects of starch synthase IIa mutations or variation on endosperm amylose content of barley, wheat and rice are determined by the distribution of starch synthase I and starch branching enzyme IIb between the starch granule and amyloplast stroma.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2015Article
- Allelic effects on starch structure and properties of six starch biosynthetic genes in a rice recombinant inbred line population.Rice (New York, N.Y.) · 2015Article
- Deficiencies in both starch synthase IIIa and branching enzyme IIb lead to a significant increase in amylose in SSIIa-inactive japonica rice seeds.Journal of experimental botany · 2014Article
- Improving cereal grain carbohydrates for diet and health.Journal of cereal science · 2014Review
- Suppression of starch synthase I expression affects the granule morphology and granule size and fine structure of starch in wheat endosperm.Journal of experimental botany · 2014Article
- New starch phenotypes produced by TILLING in barley.PloS one · 2014Article
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Abstract
In this study of barley starch synthesis, the interaction between mutations at the sex6 locus and the amo1 locus has been characterized. Four barley genotypes, the wild type, sex6, amo1, and the amo1sex6 double mutant, were generated by backcrossing the sex6 mutation present in Himalaya292 into the amo1 'high amylose Glacier'. The wild type, amo1, and sex6 genotypes gave starch phenotypes consistent with previous studies. However, the amo1sex6 double mutant yielded an unexpected phenotype, a significant increase in starch content relative to the sex6 phenotype. Amylose content (as a percentage of starch) was not increased above the level observed for the sex6 mutation alone; however, on a per seed basis, grain from lines containing the amo1 mutation (amo1 mutants and amo1sex6 double mutants) synthesize significantly more amylose than the wild-type lines and sex6 mutants. The level of granule-bound starch synthase I (GBSSI) protein in starch granules is increased in lines containing the amo1 mutation (amo1 and amo1sex6). In the amo1 genotype, starch synthase I (SSI), SSIIa, starch branching enzyme IIa (SBEIIa), and SBEIIb also markedly increased in the starch granules. Genetic mapping studies indicate that the ssIIIa gene is tightly linked to the amo1 locus, and the SSIIIa protein from the amo1 mutant has a leucine to arginine residue substitution in a conserved domain. Zymogram analysis indicates that the amo1 phenotype is not a consequence of total loss of enzymatic activity although it remains possible that the amo1 phenotype is underpinned by a more subtle change. It is therefore proposed that amo1 may be a negative regulator of other genes of starch synthesis.
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