ArticleThe New England journal of medicine2011
Emergence of a new pathogenic Ehrlichia species, Wisconsin and Minnesota, 2009.
Article in The New England journal of medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 127 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
127 citing papers in PubMed, 5 syntheses or guidelines pooled it, 289 citations in OpenAlex.
- Prevalence and associated factors of Anaplasma, Rickettsia, and Coxiella-related bacteria in ticks in China: A systematic review and meta-analysis.Experimental & applied acarology · 2026Pooled it
- Human monocytotropic ehrlichiosis-A systematic review and analysis of the literature.PLoS neglected tropical diseases · 2024Pooled it
- A Guide to Utilization of the Microbiology Laboratory for Diagnosis of Infectious Diseases: 2018 Update by the Infectious Diseases Society of America and the American Society for Microbiology.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018Guideline
- Human pathogens associated with the blacklegged tick Ixodes scapularis: a systematic review.Parasites & vectors · 2016Pooled it
- A guide to utilization of the microbiology laboratory for diagnosis of infectious diseases: 2013 recommendations by the Infectious Diseases Society of America (IDSA) and the American Society for Microbiology (ASM)(a).Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2013Guideline
- Global Trends in Vaccine Research onMicroorganisms · 2026Review
- A Molecular Epidemiological Survey of Tick-Borne Pathogens in Dogs and Their Associated Ticks in Xinjiang, China.Animals : an open access journal from MDPI · 2026Article
- Tick-Borne Co-Infection in Lyme Disease: Clinical Impact, Diagnostic Challenges, and Therapeutic Perspectives.Microorganisms · 2026Review
- Fatal Ehrlichia muris eauclairensis Infection in Liver Transplant Recipient, Minnesota, USA.Emerging infectious diseases · 2026Article
- Molecular Characterization and Epidemiology of Anaplasmataceae in Ticks and Domestic Animals in the Colombian Caribbean.Animals : an open access journal from MDPI · 2025Article
- Variety of Bacterial Pathogens in Ticks Removed from Humans, Northeastern China.Microorganisms · 2025Article
- Update on North American tick-borne diseases and how to diagnose them.Journal of clinical microbiology · 2025Review
- Behavioral manipulation ofmBio · 2025Article
- Histological staining of tick bite skin biopsies for spirochetes and Powassan virus RNA.Microbiology spectrum · 2025Article
- Ticks and Tick-Borne Pathogens Circulating in Peri-Domestic Areas in Mainland Portugal.Microorganisms · 2024Article
- Detection of Anaplasma and Ehrlichia bacteria in humans, wildlife, and ticks in the Amazon rainforest.Nature communications · 2024Article
- Article
- Emerging Tick-borne Infections in the Upper Midwest and Northeast United States Among Patients With Suspected Anaplasmosis.Open forum infectious diseases · 2024Article
- Human Tick-Borne Diseases and Advances in Anti-Tick Vaccine Approaches: A Comprehensive Review.Vaccines · 2024Review
- Tick-borne pathogens of zoonotic and veterinary importance in cattle ticks in Ghana.Parasitology research · 2023Article
67 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
25 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundEhrlichiosis is a clinically important, emerging zoonosis. Only Ehrlichia chaffeensis and E. ewingii have been thought to cause ehrlichiosis in humans in the United States. Patients with suspected ehrlichiosis routinely undergo testing to ensure proper diagnosis and to ascertain the cause.
methodsWe used molecular methods, culturing, and serologic testing to diagnose and ascertain the cause of cases of ehrlichiosis.
resultsOn testing, four cases of ehrlichiosis in Minnesota or Wisconsin were found not to be from E. chaffeensis or E. ewingii and instead to be caused by a newly discovered ehrlichia species. All patients had fever, malaise, headache, and lymphopenia; three had thrombocytopenia; and two had elevated liver-enzyme levels. All recovered after receiving doxycycline treatment. At least 17 of 697 Ixodes scapularis ticks collected in Minnesota or Wisconsin were positive for the same ehrlichia species on polymerase-chain-reaction testing. Genetic analyses revealed that this new ehrlichia species is closely related to E. muris.
conclusionsWe report a new ehrlichia species in Minnesota and Wisconsin and provide supportive clinical, epidemiologic, culture, DNA-sequence, and vector data. Physicians need to be aware of this newly discovered close relative of E. muris to ensure appropriate testing, treatment, and regional surveillance. (Funded by the National Institutes of Health and the Centers for Disease Control and Prevention.).
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.