ArticlePLoS neglected tropical diseases2011
Multi-locus sequence analysis reveals profound genetic diversity among isolates of the human pathogen Bartonella bacilliformis.
Article in PLoS neglected tropical diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Single-nucleotide polymorphisms in ialB, gltA and rpoB genes of Bartonella bacilliformis isolated from patients in endemic Peruvian regions.PLoS neglected tropical diseases · 2023Article
- Carrion's Disease: the Sound of Silence.Clinical microbiology reviews · 2018Review
- Transmission in the Origins of Bacterial Diversity, From Ecotypes to Phyla.Microbiology spectrum · 2017Article
- Whole-Genome Analysis of Bartonella ancashensis, a Novel Pathogen Causing Verruga Peruana, Rural Ancash Region, Peru.Emerging infectious diseases · 2017Article
- Article
- Prevalence and Diversity of Bartonella Species in Rodents from Georgia (Caucasus).The American journal of tropical medicine and hygiene · 2016Article
- Mutation-Driven Divergence and Convergence Indicate Adaptive Evolution of the Intracellular Human-Restricted Pathogen, Bartonella bacilliformis.PLoS neglected tropical diseases · 2016Article
- Multi-Locus Sequence Typing of Bartonella bacilliformis DNA Performed Directly from Blood of Patients with Oroya's Fever During a Peruvian Outbreak.PLoS neglected tropical diseases · 2016Article
- Proteins of Bartonella bacilliformis: Candidates for Vaccine Development.International journal of peptides · 2015Review
- Classification of Bartonella strains associated with straw-colored fruit bats (Eidolon helvum) across Africa using a multi-locus sequence typing platform.PLoS neglected tropical diseases · 2015Article
- Oroya fever and verruga peruana: bartonelloses unique to South America.PLoS neglected tropical diseases · 2014Review
- Dried blood spots for qPCR diagnosis of acute Bartonella bacilliformis infection.The American journal of tropical medicine and hygiene · 2013Article
- Molecular typing of "Candidatus Bartonella ancashi," a new human pathogen causing verruga peruana.Journal of clinical microbiology · 2013Article
- A gene transfer agent and a dynamic repertoire of secretion systems hold the keys to the explosive radiation of the emerging pathogen Bartonella.PLoS genetics · 2013Article
- Distribution of Bartonella henselae variants in patients, reservoir hosts and vectors in Spain.PloS one · 2013Article
- Article
- Reproductive clonality of pathogens: a perspective on pathogenic viruses, bacteria, fungi, and parasitic protozoa.Proceedings of the National Academy of Sciences of the United States of America · 2012Article
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3 authors.
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Abstract
Bartonella bacilliformis is the aetiological agent of human bartonellosis, a potentially life threatening infection of significant public health concern in the Andean region of South America. Human bartonellosis has long been recognised in the region but a recent upsurge in the number of cases of the disease and an apparent expansion of its geographical distribution have re-emphasized its contemporary medical importance. Here, we describe the development of a multi-locus sequence typing (MLST) scheme for B. bacilliformis and its application to an archive of 43 isolates collected from patients across Peru. MLST identified eight sequence types among these isolates and the delineation of these was generally congruent with those of the previously described typing scheme. Phylogenetic analysis based on concatenated sequence data derived from MLST loci revealed that seven of the eight sequence types were closely related to one another; however, one sequence type, ST8, exhibited profound evolutionary divergence from the others. The extent of this divergence was akin to that observed between other members of the Bartonella genus, suggesting that ST8 strains may be better considered as members of a novel Bartonella genospecies.
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