ReviewNature reviews. Urology2011
Urological aspects of the metabolic syndrome.
Review in Nature reviews. Urology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
44 citing papers in PubMed, 101 citations in OpenAlex.
- High-fat diet feeding reduced smooth muscle contractility and increasing tissue programmed death activity in rats bladder tissue.International urology and nephrology · 2026Article
- Impact of metabolic syndrome and its components on the tumor aggressiveness of renal cell carcinoma.Medicine · 2026Observational
- Association between cardiometabolic index and overactive bladder in adult American women: A cross-sectional study.PloS one · 2025Article
- Analysis of metabolic syndrome in bilateral upper urinary tract stones: A retrospective study of 3905 cases.Heliyon · 2024Article
- Effect of Diabetes Mellitus on Symptomatic Improvement After Surgery for Benign Prostatic Hyperplasia in Patients With Lower Urinary Tract Symptom and its Relations With Prostatic Urethral Angulation.International neurourology journal · 2023Article
- Simvastatin Improves Benign Prostatic Hyperplasia: Role of Peroxisome-Proliferator-Activated Receptor-γ and Classic WNT/β-Catenin Pathway.International journal of molecular sciences · 2023Article
- Prevalence and temporal trends of prostate diseases among inpatients with cardiovascular disease: a nationwide real-world database survey in Japan.Frontiers in cardiovascular medicine · 2023Article
- Leptin Mediates Prostate Stromal Cell Proliferation, Smooth Muscle Contraction, and Mitochondrial Function in Benign Prostate Hyperplasia.Diabetes, metabolic syndrome and obesity : targets and therapy · 2023Article
- Review
- Metabolic syndrome and its pharmacologic treatment are associated with the time to castration-resistant prostate cancer.Prostate cancer and prostatic diseases · 2022Article
- Premature Ejaculation and Endocrine Disorders: A Literature Review.The world journal of men's health · 2022Review
- Incidence and correlation of metabolic syndrome and kidney stones in a healthy screening population.Translational andrology and urology · 2021Article
- Metformin use and long-term risk of benign prostatic hyperplasia: a population-based cohort study.BMJ open · 2020Article
- The Role of Metabolic Factors in Renal Cancers.International journal of molecular sciences · 2020Review
- Genome-wide associations for benign prostatic hyperplasia reveal a genetic correlation with serum levels of PSA.Nature communications · 2018Article
- A stage-dependent link between metabolic syndrome components and incident prostate cancer.Nature reviews. Urology · 2018Review
- Stimulators and activators of soluble guanylate cyclase for urogenital disorders.Nature reviews. Urology · 2018Review
- Metabesity and urological cancers.Turkish journal of urology · 2017Review
- The Effect of Different Metabolic Syndrome: Definitions on the Relationship Between Metabolic Syndrome and LUTS in Men With Benign Prostatic Enlargement.American journal of men's health · 2017Article
- Parental High-Fat Diet Promotes Inflammatory and Senescence-Related Changes in Prostate.Oxidative medicine and cellular longevity · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The metabolic syndrome is common in countries with Western lifestyles. It comprises a number of disorders-including insulin resistance, hypertension and obesity-that all act as risk factors for cardiovascular diseases. Urological diseases have also been linked to the metabolic syndrome. Most established aspects of the metabolic syndrome are linked to benign prostatic hyperplasia (BPH) and prostate cancer. Fasting plasma insulin, in particular, has been linked to BPH and incident, aggressive and lethal prostate cancer. The metabolic syndrome has also been shown to be associated with nonprostatic urological conditions such as male hypogonadism, nephrolithiasis, overactive bladder and erectile dysfunction, although data on these conditions are still sparse. Overall, the results of studies on urological aspects of the metabolic syndrome seem to indicate that BPH and prostate cancer could be regarded as two new aspects of the metabolic syndrome, and that an increased insulin level is a common underlying aberration that promotes both BPH and clinical prostate cancer. Urologists need to be aware of the effect that the metabolic syndrome has on urological disorders and should transfer this knowledge to their patients.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.