Evidence map›Paper›PMID 21811137›Full record

ReviewAIDS (London, England)2011

Is expanded HIV treatment preventing new infections? Impact of antiretroviral therapy on sexual risk behaviors in the developing world.

Kartik K Venkatesh, Timothy P Flanigan, Kenneth H Mayer

Abstract readReview
In one paragraph

Review in AIDS (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kartik K VenkateshDivision of Infectious Diseases, Department of Medicine, Alpert Medical School, Brown University, Miriam Hospital, Providence, Rhode Island, USA. Kartik_Venkatesh@Brown.edu
Timothy P Flanigan
Kenneth H Mayer

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Miriam/Brown/Tufts Fogarty AIDS International Training and Research ProgramD43TW000237 · FIC · MIRIAM HOSPITAL · PI CU-UVIN, SUSAN · 1993 to 2014
$10.6M
Enhancing HIV Secondary Prevention in a clinical care setting in southern IndiaF30MH079738 · NIMH · BROWN UNIVERSITY · PI VENKATESH, KARTIK KAILAS · 2006 to 2011
$270k
FIC NIH HHS D43 TW000237FIC NIH HHS D43TW00237NIAID NIH HHS P30 AI042853NIAID NIH HHS P30AI042853NIMH NIH HHS F30 MH079738NIMH NIH HHS F30 MH079738-01A2
6 · The paper itself

Abstract

There have been dramatic increases in access to antiretroviral therapy (ART) across the developing world, and growing public health attention has focused on the possibility of utilizing ART as a means of slowing the global HIV epidemic. The preventive impact of ART will likely depend on decreasing levels of sexual risk behaviors following treatment initiation. The current review study examines the impact of wider access to ART on sexual risk behaviors among HIV-infected individuals in the developing world. The observational studies to date demonstrate that ART is associated with a significant reduction in unprotected sex following treatment initiation. Although data on the impact of ART on possible risk compensation are rapidly expanding across the developing world, more evidence is still needed before we can safely conclude expanded treatment will result in durable decreases in sexual risk behaviors.

Indexed as

Risk-TakingAnti-HIV AgentsCross-Sectional StudiesDeveloping CountriesFemaleHIV InfectionsHumansMaleUnsafe SexAnti-HIV Agents

Identifiers

PMID21811137
PMCPMC7295031

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.