ArticleInvestigative ophthalmology & visual science2011
Spatial distribution of posterior pole choroidal thickness by spectral domain optical coherence tomography.
Article in Investigative ophthalmology & visual science, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 64 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
64 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Choroidal Thickness and Its Association With Age, Axial Length, and Refractive Error in Chinese Adults.Investigative ophthalmology & visual science · 2022Pooled it
- Choroidal Thickness Profiles in Myopic Eyes of Young Adults in the Correction of Myopia Evaluation Trial Cohort.American journal of ophthalmology · 2015Trial
- Three-dimensional automated choroidal volume assessment on standard spectral-domain optical coherence tomography and correlation with the level of diabetic macular edema.American journal of ophthalmology · 2014Trial
- Evaluation of cystoid change phenotypes in ocular toxoplasmosis using optical coherence tomography.PloS one · 2014Trial
- Global choroidal thickness in healthy eyes assessed by ultra-widefield swept-source optical coherence tomography.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Defining a Novel RPGR Phenotype of Sector Retinitis Pigmentosa With Cone Dystrophy.Investigative ophthalmology & visual science · 2026Observational
- Assessment of Macular Choroidal Thickness via Enhanced Depth Imaging Optical Coherence Tomography in Patients With Chronic Tinnitus.Journal of ophthalmology · 2026Article
- Choroidal Thickness Distribution and Its Association With Axial Length and Spherical Equivalent in Schoolchildren Assessed by Wide-Field Swept-Source Optical Coherence Tomography.Translational vision science & technology · 2025Article
- Association of SDF-1-3' Gene A Variant with Diabetic Retinopathy in the Hungarian Population.International journal of molecular sciences · 2024Article
- Coefficient of spatial variance of choroidal thickness on swept-source optical coherence tomography in healthy eyes.International ophthalmology · 2024Article
- Comparison of manual and artificial intelligence-automated choroidal thickness segmentation of optical coherence tomography imaging in myopic adults.Eye and vision (London, England) · 2024Article
- Regional choroidal thickness estimation from color fundus images based on convolutional neural networks.Heliyon · 2024Article
- Quantitative Evaluation of the Topographical Maps of Three-Dimensional Choroidal Vascularity Index in Children With Different Degrees of Myopia.Investigative ophthalmology & visual science · 2024Article
- Automatic fovea detection and choroid segmentation for choroidal thickness assessment in optical coherence tomography.International journal of ophthalmology · 2024Article
- Establishment of a novel ER-stress induced myopia model in mice.Eye and vision (London, England) · 2023Article
- Ophthalmologic Phenotype-Genotype Correlations in Patients With Oculocutaneous Albinism Followed in a Reference Center.Investigative ophthalmology & visual science · 2023Observational
- New findings on choroidal features in healthy people by ultra-widefield swept-source optical coherence tomography angiography.Scientific reports · 2023Observational
- IMI-The Dynamic Choroid: New Insights, Challenges, and Potential Significance for Human Myopia.Investigative ophthalmology & visual science · 2023Review
- Within-day changes in luminal, stromal choroidal thickness, and choroidal vascularity index in healthy adults.Indian journal of ophthalmology · 2023Article
- Corneal morphology correlates with choriocapillaris perfusion in myopic children.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2022Article
4 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
9 authors.
Funding
Abstract
purposeTo study the spatial distribution of posterior pole choroidal thickness (CT) in healthy eyes using spectral domain optical coherence tomography (SD-OCT).
methodsFifty-nine eyes from 30 subjects with no retinal or choroidal disease were examined with high-definition (HD) OCT using macular volume cube scanning protocols. A randomly chosen subset also had multifield analysis performed (volume scans centered on and surrounding the optic nerve head [ONH]). CT was manually quantified using a validated reading center tool. For macular scans, mean CT was calculated for each Early Treatment Diabetic Retinopathy Study subfield. Compound posterior pole CT maps were also created through the alignment of OCT projection images. Regression analyses were used to evaluate the correlation between CT and axial length (AL), refractive error, age, sex, and ethnicity.
resultsSubfoveal CT was 297.8 ± 82.2 μm, which did not differ significantly from that of the inner macular subfields. CT was greatest in the superior outer subfield and thinnest in the nasal outer subfield. The most predictive models for macular CT included AL and/or age. Outside the macula, CT was thinnest inferonasal to the ONH.
conclusionsCT demonstrates large variations between individuals, but also at different locations within the posterior pole; substantial choroidal thinning inferonasal to the ONH was demonstrated. CT appears to correlate more with distance from the optic nerve than from the fovea and, thus, in future studies, the ONH may serve as a better reference point than the foveal center for expressing or depicting regional CT variations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.