Evidence map›Paper›PMID 21810556›Full record

ReviewEnvironmental health perspectives2011

Health effects of naturally radioactive water ingestion: the need for enhanced studies.

Irina Guseva Canu, Olivier Laurent, Nathalie Pires, Dominique Laurier, Isabelle Dublineau

Open access · diamondAbstract readReview
In one paragraph

Review in Environmental health perspectives, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
5.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 104 citations in OpenAlex.

  1. Natural radioactivity in Brazil: a systematic review.Environmental science and pollution research international · 2020
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Once upon a mine: the legacy of uranium on the Navajo Nation.Environmental health perspectives · 2014
    Article
  15. Article
  16. Article
  17. Review
  18. Unknown quantity: regulating radionuclides in tap water.Environmental health perspectives · 2012
    Article
  19. Survey ofAWWA water science
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Irina Guseva CanuService de Radiobiologie et Epidémiologie, Institut de Radioprotection et de Sûreté Nucléaire, Fontenay-aux-Roses, France irina.canu@irsn.fr
Olivier Laurent
Nathalie Pires
Dominique Laurier
Isabelle Dublineau
Service de la Santé Publique · CHInstitut de Radioprotection et de Sûreté Nucléaire · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRadiological pollution is a potentially important aspect of water quality. However, relatively few studies have been conducted to document its possible health effects.

objectiveIn this commentary we discuss available epidemiological findings and related data from experimental studies concerning the health effects of naturally radioactive water ingestion. DISCUSSION: Despite modest epidemiological evidence of uranium nephrotoxicity and radium effects on bone, available data are not sufficient to quantify the health effects of naturally occurring radionuclides in water. Methodological limitations (exposure measurement methods, control for confounding, sample size) affect most studies. Power calculations should be conducted before launching new epidemiological studies focusing on late pathological outcomes. Studies based on biomarkers of exposure and adverse effects may be helpful but should involve more specific molecules than biomarkers used in previous studies. Experimental data on ingestion of drinking water are limited to uranium studies, and there is some disagreement between these studies about the nephrotoxicity threshold.

conclusionFurther experimental and enhanced epidemiological studies should help to reduce uncertainties resulting from dose estimation to dose-response characterization.

Indexed as

Epidemiologic MethodsResearchEnvironmental HealthHumansRadioisotopesWater Pollutants, RadioactiveWater QualityRadioisotopesWater Pollutants, Radioactive

Identifiers

PMID21810556
PMCPMC3261972
OpenAlexW2048469687

What OpenQuestion holds

Textmetadata
LicenceCC0
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.