ReviewSeminars in oncology2011
Beyond standard adjuvant therapy for colon cancer: role of nonstandard interventions.
Review in Seminars in oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 33 citations in OpenAlex.
- Study protocol for "Moving Bright, Eating Smart"- A phase 2 clinical trial on the acceptability and feasibility of a diet and physical activity intervention to prevent recurrence in colorectal cancer survivors.BMC public health · 2013Trial
- The Role of Plant-Based Diets for Cancer Survivors and Planetary Health.Current oncology (Toronto, Ont.) · 2026Review
- Diet and physical activity in colorectal cancer patients: A research protocol of a randomized controlled study.World journal of gastrointestinal oncology · 2025Article
- Association of Prediagnosis Obesity and Postdiagnosis Aspirin With Survival From Stage IV Colorectal Cancer.JAMA network open · 2022Article
- Let food be thy medicine: the role of diet in colorectal cancer: a narrative review.Journal of gastrointestinal oncology · 2022Review
- Evidence-based nutrition guidelines for cancer survivors in Europe: a call for action.European journal of clinical nutrition · 2022Article
- A pilot study of a low glycemic load diet in patients with stage I-III colorectal cancer.Journal of gastrointestinal oncology · 2021Article
- Post-cancer diagnosis dietary inflammatory potential is associated with survival among women diagnosed with colorectal cancer in the Women's Health Initiative.European journal of nutrition · 2020Article
- The effect of strength and endurance training on SSTR2 and SSTR5 in patients with colorectal cancer.Journal of exercise rehabilitation · 2019Article
- Weight loss following diet-induced obesity does not alter colon tumorigenesis in the AOM mouse model.American journal of physiology. Gastrointestinal and liver physiology · 2016Article
- Impact of regular aspirin use on overall and cancer-specific survival in patients with colorectal cancer harboring a PIK3CA mutation.Acta oncologica (Stockholm, Sweden) · 2015Article
- Article
- Making lifestyle changes after colorectal cancer: insights for program development.Current oncology (Toronto, Ont.) · 2013Article
- Association between red and processed meat intake and mortality among colorectal cancer survivors.Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2013Article
- Targeting tumor microenvironment with silibinin: promise and potential for a translational cancer chemopreventive strategy.Current cancer drug targets · 2013Review
- Diet and nutrition in cancer survivorship and palliative care.Evidence-based complementary and alternative medicine : eCAM · 2013Review
- OSU-03012 suppresses GRP78/BiP expression that causes PERK-dependent increases in tumor cell killing.Cancer biology & therapy · 2012Article
- Impact of Diet, Body Mass Index, and Physical Activity on Cancer Survival.Current nutrition reports · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Epidemiologic and scientific research indicates that diet and other lifestyle factors have a significant influence on the risk of developing colorectal cancer. Obesity, consumption of red meat, a Western pattern diet, alcohol, and smoking influence one's risk of developing colorectal cancer while physical activity, vitamin D, postmenopausal estrogen use, aspirin, and nonsteroidal anti-inflammatory drugs (NSAIDs) decrease one's risk. Until recently, it was largely unknown if any of these modifiable factors influence the outcomes of patients already diagnosed with colorectal cancer. However, data are emerging of factors that may influence disease recurrences and mortality for colorectal cancer survivors. Prospective observational studies have shown that increased exercise after diagnosis and avoidance of a Western pattern diet are associated with reduced risk of cancer recurrence and improved overall survival in early-stage colorectal cancer after standard therapy. Patients with class II and III obesity (body mass index [BMI] ≥35 kg/m(2)) have a modestly increased risk of recurrence. Regular use of aspirin or cyclooxygenase (COX)-2 inhibitors decrease recurrence rates and increase serum vitamin D levels. In contrast, change of weight after diagnosis or smoking status (never, past, or current) are not associated with outcomes after diagnosis. The data supporting these observations will be reviewed, potential mechanisms of actions will be discussed, and the next steps forward will be proposed.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.