Evidence map›Paper›PMID 21810242›Full record

Trial reportImplementation science : IS2011

Task shifting and integration of HIV care into primary care in South Africa: the development and content of the streamlining tasks and roles to expand treatment and care for HIV (STRETCH) intervention.

Kerry E Uebel, Lara R Fairall, Dingie Hcj van Rensburg, Willie F Mollentze, Max O Bachmann, Simon Lewin, Merrick Zwarenstein, Christopher J Colvin, Daniella Georgeu, Pat Mayers and 3 more

Registry-linked trialAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Implementation science : IS, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05671718 (Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment in Primary Care to Physician-Led, Hospital-Based Outpatient RR-TB Treatment), which is not on this map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05671718 narecruitingnot on this mapstarted 2023, after this paper: background citation

Bring BPaL2Me Trial Comparing Nurse-Led RR-TB Treatment in Primary Care to Physician-Led, Hospital-Based Outpatient RR-TB Treatment: A Cluster Randomized, Non-Inferiority Trial

TypeinterventionalSponsorJohns Hopkins UniversityRan2023 to 2030Enrolled2,944ConditionsDrug Resistant TuberculosisArmsNurse-Led Treatment in Primary Care
3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2026
    Pooled it
  2. Tailored interventions to address determinants of practice.The Cochrane database of systematic reviews · 2015
    Pooled it
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  13. Observational
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  18. Antiretroviral therapy for the prevention of HIV transmission: what will it take?Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Kerry E UebelKnowledge Translation Unit, University of Cape Town Lung Institute, University of Cape Town, Cape Town, South Africa.
Lara R Fairall
Dingie Hcj van Rensburg
Willie F Mollentze
Max O Bachmann
Simon Lewin
Merrick Zwarenstein
Christopher J Colvin
Daniella Georgeu
Pat Mayers
Gill M Faris
Carl Lombard
Eric D Bateman

Funding

Medical Research Council G0800605
6 · The paper itself

Abstract

backgroundTask shifting and the integration of human immunodeficiency virus (HIV) care into primary care services have been identified as possible strategies for improving access to antiretroviral treatment (ART). This paper describes the development and content of an intervention involving these two strategies, as part of the Streamlining Tasks and Roles to Expand Treatment and Care for HIV (STRETCH) pragmatic randomised controlled trial.

methodsDEVELOPING THE

interventionThe intervention was developed following discussions with senior management, clinicians, and clinic staff. These discussions revealed that the establishment of separate antiretroviral treatment services for HIV had resulted in problems in accessing care due to the large number of patients at ART clinics. The intervention developed therefore combined the shifting from doctors to nurses of prescriptions of antiretrovirals (ARVs) for uncomplicated patients and the stepwise integration of HIV care into primary care services.

resultsCOMPONENTS OF THE

interventionThe intervention consisted of regulatory changes, training, and guidelines to support nurse ART prescription, local management teams, an implementation toolkit, and a flexible, phased introduction. Nurse supervisors were equipped to train intervention clinic nurses in ART prescription using outreach education and an integrated primary care guideline. Management teams were set up and a STRETCH coordinator was appointed to oversee the implementation process. DISCUSSION: Three important processes were used in developing and implementing this intervention: active participation of clinic staff and local and provincial management, educational outreach to train nurses in intervention sites, and an external facilitator to support all stages of the intervention rollout.The STRETCH trial is registered with Current Control Trials ISRCTN46836853.

Indexed as

Ambulatory Care FacilitiesAnti-HIV AgentsDelivery of Health CareEducation, Nursing, ContinuingHIV InfectionsHumansNurse's RolePrimary Health CareSouth AfricaAnti-HIV Agents

Identifiers

PMID21810242
PMCPMC3163620

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.