When will thyrotropin receptor antagonists and inverse thyrotropin receptor agonists become available for clinical use?

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

Who cites it

7 citing papers in PubMed.

1. Precision Medicine in Graves' Disease and Ophthalmopathy.Frontiers in pharmacology · 2021
   Review
2. Practical applications of studies on the TSH receptor and TSH receptor autoantibodies.Endocrine · 2020
   Article
3. Preclinical studies on the toxicology, pharmacokinetics and safety of K1-70Auto- immunity highlights · 2019
   Article
4. A decade of thyroidology.Hormones (Athens, Greece) · 2018
   Review
5. Synthetic gene network restoring endogenous pituitary-thyroid feedback control in experimental Graves' disease.Proceedings of the National Academy of Sciences of the United States of America · 2016
   Article
6. A selective TSH receptor antagonist inhibits stimulation of thyroid function in female mice.Endocrinology · 2014
   Article
7. A drug-like antagonist inhibits thyrotropin receptor-mediated stimulation of cAMP production in Graves' orbital fibroblasts.Thyroid : official journal of the American Thyroid Association · 2012
   Article

Corrections and comments

• Comment on
  Small-molecule thyrotropin receptor agonist activates naturally occurring thyrotropin-insensitive mutants and reveals their distinct cyclic adenosine monophosphate signal persistence.2011

Authors and funding

1 author.

Funding

No grant is acknowledged in the PubMed record.

Abstract

PubMed holds no abstract for this paper.

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