ArticleNanotoxicology2012
A novel platform for pulmonary and cardiovascular toxicological characterization of inhaled engineered nanomaterials.
Article in Nanotoxicology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.
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Who cites it
35 citing papers in PubMed.
- SiOScientific reports · 2025Article
- Effective density of inhaled environmental and engineered nanoparticles and its impact on the lung deposition and dosimetry.Particle and fibre toxicology · 2024Article
- Silica encapsulation of ZnO nanoparticles reduces their toxicity for cumulus cell-oocyte-complex expansion.Particle and fibre toxicology · 2021Article
- Environmentally Relevant Iron Oxide Nanoparticles Produce Limited Acute Pulmonary Effects in Rats at Realistic Exposure Levels.International journal of molecular sciences · 2021Article
- Human brain microvascular endothelial cell pairs model tissue-level blood-brain barrier function.Integrative biology : quantitative biosciences from nano to macro · 2020Article
- Integrated Transcriptomics, Metabolomics, and Lipidomics Profiling in Rat Lung, Blood, and Serum for Assessment of Laser Printer-Emitted Nanoparticle Inhalation Exposure-Induced Disease Risks.International journal of molecular sciences · 2019Article
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- Evaluation of tumorigenic potential of CeONanoImpact · 2017Article
- Anodically Grown Titania Nanotube Induced Cytotoxicity has Genotoxic Origins.Scientific reports · 2017Article
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- Thermal decomposition of nano-enabled thermoplastics: Possible environmental health and safety implications.Journal of hazardous materials · 2016Article
- Effects of Laser Printer-Emitted Engineered Nanoparticles on Cytotoxicity, Chemokine Expression, Reactive Oxygen Species, DNA Methylation, and DNA Damage: A Comprehensive in Vitro Analysis in Human Small Airway Epithelial Cells, Macrophages, and Lymphoblasts.Environmental health perspectives · 2016Article
- Short-term exposure to engineered nanomaterials affects cellular epigenome.Nanotoxicology · 2016Article
- Performance of Particulate Containment at Nanotechnology Workplaces.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2015Article
- Advanced computational modeling for in vitro nanomaterial dosimetry.Particle and fibre toxicology · 2015Article
- An integrated methodology for the assessment of environmental health implications during thermal decomposition of nano-enabled products.Environmental science. Nano · 2015Article
- Article
- Consumer exposures to laser printer-emitted engineered nanoparticles: A case study of life-cycle implications from nano-enabled products.Nanotoxicology · 2015Article
Corrections and comments
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Authors and funding
7 authors.
Funding
Abstract
A novel method is presented which is suitable for assessing in vivo the link between the physicochemical properties of engineered nanomaterials (ENM) and their biological outcomes. The ability of the technique to generate a variety of industry-relevant, property-controlled ENM exposure atmospheres for inhalation studies was systematically investigated. The primary particle size for Fe(2)O(3), SiO(2), Ag and Ag/SiO(2) was controlled from 4 to 25 nm, while the corresponding agglomerate mobility diameter of the aerosol was also controlled and varied from 40 to 120 nm. The suitability of the technique to characterize the pulmonary and cardiovascular effects of inhaled ENMs in intact animal models is also demonstrated using in vivo chemiluminescence (IVCL). The IVCL technique is a highly sensitive method for identifying cardiopulmonary responses to inhaled ENMs under relatively small doses and acute exposures. It is shown that moderate and acute exposures to inhaled nanostructured Fe(2)O(3) can cause both pulmonary and cardiovascular effects.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.