Evidence map›Paper›PMID 21809007›Full record

ReviewPflugers Archiv : European journal of physiology2011

Aquaporins as gas channels.

Marcela Herrera, Jeffrey L Garvin

Abstract readReview
PubMed Publisher
In one paragraph

Review in Pflugers Archiv : European journal of physiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 87 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Transport Characteristics of Aquaporins.Advances in experimental medicine and biology · 2023
    Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. A novel molecular dynamics study of COThe European physical journal. E, Soft matter · 2019
    Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Aquaporin Protein-Protein Interactions.International journal of molecular sciences · 2017
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Marcela HerreraHypertension and Vascular Research Division, Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, USA. marcela.herrera@duke.edu
Jeffrey L Garvin
Henry Ford Hospital · USWayne State University · US

Funding

VASOACTIVE HORMONES IN THE REGULATION OF BLOOD PRESSUREP01HL028982 · NHLBI · HENRY FORD HOSPITAL · PI ORTIZ, PABLO A. · 1985 to 2017
$39.8M
Role of the kidneys in hypertension: paracrine actions of NO in the renal medullaF32DK081333 · NIDDK · HENRY FORD HEALTH SYSTEM · PI HERRERA, MARIA MARCELA · 2008 to 2010
$150k
TUMOR NECROSIS FACTOR, EICOSANOIDS AND LUNG INJURYF32HL007985 · NHLBI · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI KRUSE-ELLIOTT, KRIS · 1988 to 1991
–
HORMONAL REGULATION OF DYSFUNCTIONAL ENDOTHELIAL CELLSF32HL009550 · NHLBI · OHIO STATE UNIVERSITY · PI ROOS, CHRISTINE M · 1996 to 1997
–
NHLBI NIH HHS HL 07985NHLBI NIH HHS HL 09550NHLBI NIH HHS HL 28982NIDDK NIH HHS DK081333-01
6 · The paper itself

Abstract

Gas molecules play important roles in human physiology. Volatile substances produced by one cell often regulate neighboring cells in a paracrine fashion. While gaseous molecules have traditionally been thought to travel from cell to cell by free diffusion through the bilayer portion of the membrane, this does not explain their rapid physiological actions. The recent observations that: (1) water channels can transport other molecules besides water, and (2) aquaporins are often expressed in tissues where gas (but not water) transport is essential suggest that these channels conduct physiologically important gases in addition to water. This review summarizes recent findings on the role of aquaporins as gas transporters as well as their physiological significance.

Indexed as

AmmoniaAnimalsAquaporinsBiological TransportCarbon DioxideGasesHumansNitric OxideWaterAmmoniaAquaporinsCarbon DioxideGasesNitric OxideWater

Identifiers

PMID21809007
OpenAlexW2074618102

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.