ReviewStem cell reviews and reports2012
Epigenetic control of embryonic stem cell differentiation.
Review in Stem cell reviews and reports, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Derivation of Embryonic Stem Cells from an Endangered Cattle Breed via Somatic Cell Nuclear Transfer.Cells · 2026Article
- Application of Platelet-Rich Plasma as a Stem Cell Treatment - an Attempt to Clarify a Common Public Misconception.Current molecular medicine · 2024Review
- PKC inhibitors regulate stem cell self-renewal by regulating H3K27me3 and H3K9me3.American journal of translational research · 2022Article
- An Insight into Reprogramming Barriers to iPSC Generation.Stem cell reviews and reports · 2020Review
- Osteoblast suppression in multiple myeloma bone disease.Journal of bone oncology · 2018Review
- Epigenome-wide association study (EWAS) of BMI, BMI change and waist circumference in African American adults identifies multiple replicated loci.Human molecular genetics · 2015Article
- The roles and regulation of Polycomb complexes in neural development.Cell and tissue research · 2015Review
- Modification of genetic influences on adiposity between 36 and 63 years of age by physical activity and smoking in the 1946 British Birth Cohort Study.Nutrition & diabetes · 2014Article
- Otx2 and Oct4 drive early enhancer activation during embryonic stem cell transition from naive pluripotency.Cell reports · 2014Article
- Genome-wide age-related changes in DNA methylation and gene expression in human PBMCs.Age (Dordrecht, Netherlands) · 2014Article
- Epigenetic switching by the metabolism-sensing factors in the generation of orexin neurons from mouse embryonic stem cells.The Journal of biological chemistry · 2013Article
- The positive association of obesity variants with adulthood adiposity strengthens over an 80-year period: a gene-by-birth year interaction.Human heredity · 2013Article
- MiR-125b orchestrates cell proliferation, differentiation and migration in neural stem/progenitor cells by targeting Nestin.BMC neuroscience · 2012Article
- Article
- Article
- Stem-cell therapy and platelet-rich plasma in regenerative medicines: A review on pros and cons of the technologies.Journal of oral and maxillofacial pathology : JOMFPReview
- Functional O-GlcNAc modifications: implications in molecular regulation and pathophysiology.Critical reviews in biochemistry and molecular biologyReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pluripotent embryonic stem cells can give rise to almost all somatic cell types but this characteristic requires precise control of their gene expression patterns. The necessity of keeping the entire genome "poised" to enter into any of a number of developmental possibilities requires a unique and highly plastic chromatin organisation based around specific patterns of histone modifications although this state of affairs is normally short lived during embryonic development. By deriving embryonic stem cells from the early embryo, we can preserve the highly specialised genome organisation and this has permitted several detailed investigations into the molecular basis of pluripotency.
Indexed as
Identifiers
21808982What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.