ArticleEvidence-based complementary and alternative medicine : eCAM2012
Effect of Curcumin Against Proteus mirabilis During Crystallization of Struvite from Artificial Urine.
Article in Evidence-based complementary and alternative medicine : eCAM, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 41 citations in OpenAlex.
- Surface modification of urinary catheters with antibiofilm nanocoating: curcumin modified silver nanoparticles against Proteus mirabilis.Journal of materials science. Materials in medicine · 2026Article
- The Role of Copper in Struvite Formation in the Context of Infection Urinary Stones: A Journey at the Interface of Physics, Chemistry and Microbiology.Molecules (Basel, Switzerland) · 2026Article
- TargetingFrontiers in cellular and infection microbiology · 2025Article
- Understanding the role of zinc ions on struvite nucleation and growth in the context of infection urinary stones.Metallomics : integrated biometal science · 2024Article
- Prediction of microbe-drug associations based on a modified graph attention variational autoencoder and random forest.Frontiers in microbiology · 2024Article
- Consumption of soft drinks rich in phosphoric acid versus struvite crystallization from artificial urine.Scientific reports · 2022Article
- Aggregation of poorly crystalline and amorphous components of infectious urinary stones is mediated by bacterial lipopolysaccharide.Scientific reports · 2019Article
- Article
- Biomimetic synthesis of struvite with biogenic morphology and implication for pathological biomineralization.Scientific reports · 2015Article
- Renal struvite stones--pathogenesis, microbiology, and management strategies.Nature reviews. Urology · 2014Review
- An emerging translational model to screen potential medicinal plants for nephrolithiasis, an independent risk factor for chronic kidney disease.Evidence-based complementary and alternative medicine : eCAM · 2014Article
- Vitamin C inhibits crystallization of struvite from artificial urine in the presence of Pseudomonas aeruginosa.International braz j urol : official journal of the Brazilian Society of UrologyArticle
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We investigated the activity of curcumin against Proteus mirabilis and the struvite crystallization in relation to urinary stones formation. In order to evaluate an activity of curcumin we performed an in vitro experiment of struvite growth from artificial urine. The crystallization process was induced by Proteus mirabilis to mimic the real urinary tract infection, which usually leads to urinary stone formation. The results demonstrate that curcumin exhibits the effect against Proteus mirabilis inhibiting the activity of urease-an enzyme produced by these microorganisms. Addition of curcumin increases the induction time and decreases the efficiency of growth of struvite compared with the absence of curcumin. Interestingly, the addition of curcumin does not affect the crystal morphology and habit. In conclusion, curcumin has demonstrated its significant potential to be further investigated for its use in the case of struvite crystallization induced for the growth by Proteus mirabilis in relation to urinary stone formation.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.