ReviewNature reviews. Nephrology2011
Encapsulating peritoneal sclerosis: the state of affairs.
Review in Nature reviews. Nephrology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 103 citations in OpenAlex.
- Risk factors for Encapsulating Peritoneal Sclerosis in patients undergoing peritoneal dialysis: A meta-analysis.PloS one · 2022Pooled it
- Genetic Polymorphisms and Peritoneal Membrane Function.Peritoneal dialysis international : journal of the International Society for Peritoneal DialysisPooled it
- A case of encapsulating peritoneal sclerosis associated with tuberculous peritonitis.Clinical journal of gastroenterology · 2026Article
- From Endometriosis to Encapsulation: A Case Report of Endometriosis Causing Sclerosing Encapsulating Peritonitis.Case reports in obstetrics and gynecology · 2026Article
- The epidemiology of encapsulating peritoneal sclerosis in an era of biocompatible neutral peritoneal dialysis solution in Japan.Clinical and experimental nephrology · 2025Article
- Text mining for case report articles on "peritoneal dialysis" from PubMed database.Therapeutic apheresis and dialysis : official peer-reviewed journal of the International Society for Apheresis, the Japanese Society for Apheresis, the Japanese Society for Dialysis Therapy · 2025Article
- Pressure induces peritoneal fibrosis and inflammation through CD44 signaling.Renal failure · 2024Article
- Peritoneal Dialysis-Induced Encapsulating Peritonitis: Diagnostic and Therapeutic Challenges in Women with Benign Gynecological Pathology.Journal of clinical medicine · 2024Article
- Renal hyperparathyroidism- a risk factor in the development of encapsulating peritoneal sclerosis.Frontiers in endocrinology · 2024Article
- Mesentery stiffness changes in a patient with encapsulated peritoneal sclerosis by real-time shear-wave elastography ultrasound with histological reference.Renal failure · 2023Article
- Concurrent development of encapsulating peritoneal sclerosis and calciphylaxis in a patient with peritoneal dialysis for end-stage renal disease.BMJ case reports · 2022Article
- [Standardized histomorphological processing of peritoneal biopsies as part of the German Peritoneal Biopsy Registry (GRIP, German registry in PD)].Der Pathologe · 2020Article
- 10-year-long survival in a PD patient with severe calcifying encapsulating peritoneal sclerosis treated with tamoxifen: a case-report.BMC nephrology · 2020Article
- Efficacy of adalimumab therapy in experimental rat sclerosing encapsulated peritonitis model.Croatian medical journal · 2019Article
- miR-200c Prevents TGF-β1-Induced Epithelial-to-Mesenchymal Transition and Fibrogenesis in Mesothelial Cells by Targeting ZEB2 and Notch1.Molecular therapy. Nucleic acids · 2019Article
- Congenital peritoneal encapsulation: A review and novel classification system.World journal of gastroenterology · 2019Review
- Severe peritoneal sclerosis after repeated pressurized intraperitoneal aerosol chemotherapy with oxaliplatin (PIPAC OX): report of two cases and literature survey.Clinical & experimental metastasis · 2018Review
- The peritoneal sieving of sodium: a simple and powerful test to rule out the onset of encapsulating peritoneal sclerosis in patients undergoing peritoneal dialysis.Journal of nephrology · 2018Article
- Incidence and outcomes of encapsulating peritoneal sclerosis (EPS) and factors associated with severe EPS.PloS one · 2018Article
- Prominent Levels of the Profibrotic Chemokine CCL18 during Peritonitis:BioMed research international · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Encapsulating peritoneal sclerosis (EPS) is a severe complication of long-term peritoneal dialysis (PD) with a 50% mortality rate. EPS is characterized by progressive and excessive fibrotic thickening of the peritoneum, leading to encapsulation of the bowels and intestinal obstruction. At present, EPS cannot be detected with certainty during its early stages; however, a progressive loss of ultrafiltration capacity often precedes its development. Studies that attempted to elucidate the pathogenesis of EPS have shown that the duration of exposure to PD fluids is the most important risk factor for EPS, and that young age and possibly the effects of peritonitis are additional contributory factors. The pathophysiology of EPS is probably best described as a multiple-hit process with a central role for transforming growth factor β. A form of EPS that develops shortly after kidney transplantation has also been recognized as a distinct clinical entity, and may be a common form of EPS in countries with a high transplantation rate. Criteria have been developed to identify EPS by abdominal CT scan at the symptomatic stage, but further clinical research is needed to identify early EPS in asymptomatic patients, to clarify additional risk factors for EPS and to define optimal treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.