Evidence map›Paper›PMID 21806928›Full record

ArticleBiophysical journal2011

Multiple-timescale dynamics underlying spontaneous oscillations of saccular hair bundles.

Yuttana Roongthumskul, Lea Fredrickson-Hemsing, Albert Kao, Dolores Bozovic

Abstract read
In one paragraph

Article in Biophysical journal, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Electrical Control of the Transduction Channels' Gating Force in Mechanosensory Hair Cells.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Article
  3. Article
  4. Vestibular Drop Attacks and Meniere's Disease as Results of Otolithic Membrane Damage-A Numerical Model.Journal of the Association for Research in Otolaryngology : JARO · 2023
    Article
  5. Article
  6. Article
  7. Active Biomechanics of Sensory Hair Bundles.Cold Spring Harbor perspectives in medicine · 2019
    Review
  8. Homeostatic enhancement of sensory transduction.Proceedings of the National Academy of Sciences of the United States of America · 2017
    Article
  9. Voltage-Mediated Control of Spontaneous Bundle Oscillations in Saccular Hair Cells.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2015
    Article
  10. Control of a hair bundle's mechanosensory function by its mechanical load.Proceedings of the National Academy of Sciences of the United States of America · 2015
    Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. The diverse effects of mechanical loading on active hair bundles.Proceedings of the National Academy of Sciences of the United States of America · 2012
    Article
  16. Article
  17. Magnetic actuation of hair cells.Applied physics letters · 2011
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yuttana RoongthumskulDepartment of Physics and Astronomy and California Nanosystems Institute, University of California, Los Angeles, California, USA.
Lea Fredrickson-Hemsing
Albert Kao
Dolores Bozovic

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spontaneous oscillations displayed by hair bundles of the bullfrog sacculus have complex temporal profiles, not fully captured by single limit-cycle descriptions. Quiescent intervals are typically interspersed with oscillations, leading to a bursting-type behavior. Temporal characteristics of the oscillation are strongly affected by imposing a mechanical load or by the application of a steady-state deflection to the resting position of the bundle. Separate spectral components of the spontaneous motility are differently affected by increases in the external calcium concentration. We use numerical modeling to explore the effects of internal parameters on the oscillatory profiles, and to reproduce the experimental modulation induced by mechanical or ionic manipulation.

Indexed as

Models, BiologicalAnimalsBiomechanical PhenomenaCalciumHair Cells, AuditoryPeriodicityRana catesbeianaSaccule and UtricleTime FactorsCalcium

Identifiers

PMID21806928
PMCPMC3145268

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.