ArticleJournal of toxicology2011
Metals and breast cancer: risk factors or healing agents?
Article in Journal of toxicology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 2 syntheses or guidelines pooled it, 58 citations in OpenAlex.
- Chromium as a Risk Factor for Breast Cancer: A Meta-Analysis.Asian Pacific journal of cancer prevention : APJCP · 2022Pooled it
- Post-GWAS gene-environment interplay in breast cancer: results from the Breast and Prostate Cancer Cohort Consortium and a meta-analysis on 79,000 women.Human molecular genetics · 2014Pooled it
- Cancer and Environmental Xenobiotics: Mechanisms, Controversies, and Innovations.Journal of xenobiotics · 2025Review
- Trace element imbalances in selenium and mercury in relation to mammographic density and breast cancer progression: a case‒control study.Scientific reports · 2025Article
- Association of Occupational and Lifestyle Factors with Mammography-Detected Breast Neoplasia.Medical journal of the Islamic Republic of Iran · 2025Article
- Investigating phenotypic plasticity due to toxicants with exposure disparities in primary human breast cellsFrontiers in oncology · 2024Article
- Review
- Chromium and lead levels and alteration in DDPH inhibition in patients with breast cancer undergoing chemotherapy.Caspian journal of internal medicine · 2023Article
- Association between trace elements in cancerous and non-cancerous tissues with the risk of breast cancers in western Iran.Environmental science and pollution research international · 2022Article
- Integration of proteomic and metabolomic analyses: New insights for mapping informal workers exposed to potentially toxic elements.Frontiers in public health · 2022Article
- Heavy metals interfere with plasma metabolites, including lipids and amino acids, in patients with breast cancer.Oncology letters · 2020Article
- Evaluation of heavy metals and metabolites in the urine of patients with breast cancer.Oncology letters · 2020Article
- Elemental bioimaging shows mercury and other toxic metals in normal breast tissue and in breast cancers.PloS one · 2020Article
- Biochemical and biophysical study of chemopreventive and chemotherapeutic anti-tumor potential of some Egyptian plant extracts.Biochemistry and biophysics reports · 2019Article
- Heavy Metals in California Women Living in a Gold Mining-Impacted Community.International journal of environmental research and public health · 2019Article
- Serum Trace Elements and Their Associations with Breast Cancer Subgroups in Korean Breast Cancer Patients.Nutrients · 2018Article
- Toxic elements as biomarkers for breast cancer: a meta-analysis study.Cancer management and research · 2018Review
- Targeting Intracellular Calcium Signaling ([CaCancers · 2017Review
- Metals in Fishes from Yongshu Island, Southern South China Sea: Human Health Risk Assessment.Journal of toxicology · 2017Article
- Magnesium, zinc, arsenic, selenium and platinum urinary excretion from cancer patients of Antofagasta region, Chile: multi-metal approach.JRSM open · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Metals and metal compounds are part of our environment. Several metals are essential for physiological functions (e.g., zinc or magnesium); while the beneficial effects of others are uncertain (e.g., manganese), some metals are proven to be toxic (e.g., mercury, lead). Additionally there are organic metal compounds; some of them are extremely toxic (e.g., trimethyltin, methylmercury), but there is very little knowledge available how they are handled by organisms. Scientific evidence indicates that long-term exposure to (some) metallic compounds induces different forms of cancer, including breast cancer. On the other side, several metal compounds have clinical use in treating life-threatening diseases such as cancer. In this paper we discuss the recent literature that shows a correlation between metal exposure and breast cancer.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.