Evidence map›Paper›PMID 21803281›Full record

ArticleCell metabolism2011

Anaerobicizing into pluripotency.

Athanasia D Panopoulos, Juan Carlos Izpisua Belmonte

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cell metabolism, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Metabolic circuits in neural stem cells.Cellular and molecular life sciences : CMLS · 2014
    Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Energy metabolism plasticity enables stemness programs.Annals of the New York Academy of Sciences · 2012
    Review
  14. Mitochondria in control of cell fate.Circulation research · 2012
    Article
  15. Energy metabolism in nuclear reprogramming.Biomarkers in medicine · 2011
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Athanasia D PanopoulosGene Expression Laboratory, The Salk Institute for Biological Studies, La Jolla, CA 92037, USA.
Juan Carlos Izpisua Belmonte

Funding

Viral Vector Core (VVC)P30CA014195 · NCI · SALK INSTITUTE FOR BIOLOGICAL STUDIES · PI Reuben Shaw · 1985 to 2026
$82.8M
6 · The paper itself

Abstract

Reprogramming involves multiple layers of molecular regulation, yet it remains relatively unknown how the cell's metabolism is changing and/or contributing to this process. In this issue of Cell Metabolism, Folmes et al. (2011) demonstrate that reprogramming induces a bioenergetic transition from an oxidative to a glycolytic state, and provide evidence to suggest that these changes may precede pluripotency.

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.