ArticleEmerging infectious diseases2011
Novel human reovirus isolated from children with acute necrotizing encephalopathy.
Article in Emerging infectious diseases, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers.
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Who cites it
72 citing papers in PubMed.
- Molecular detection of zoonotic RNA viruses in guinea pigs (One health (Amsterdam, Netherlands) · 2026Article
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- Molecular survey of mammalian orthoreovirus and Rotavirus A in Italian dogs and cats.Frontiers in veterinary science · 2026Article
- Ataxin-2-like promotes translation of nonpolyadenylated reovirus mRNA.Nature communications · 2025Article
- Isolation and characterization of a novel reassortant strain of Orthoreovirus mammalis from diarrheic pig.Virus genes · 2025Article
- Genomic characterization of arboviruses discovered between the 1950s and 1980s.Journal of virology · 2025Article
- Identification of Reassortant Mammalian Orthoreovirus Strains in European Hedgehogs (Microorganisms · 2025Article
- Genomic Characteristics and Pathogenicity of Novel Reassortant Mammalian Orthoreoviruses From Sheep, China.Transboundary and emerging diseases · 2025Article
- First report on the identification and characterization of mammalian orthoreovirus from sheep in China.Microbiology spectrum · 2024Article
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- Reovirus infection induces transcriptome-wide unique A-to-I editing changes in the murine fibroblasts.Virus research · 2024Article
- First Specific Detection of Mammalian Orthoreovirus from Goats Using TaqMan Real-Time RT-PCR Technology.Veterinary sciences · 2024Article
- Structure of orthoreovirus RNA chaperone σNS, a component of viral replication factories.Nature communications · 2024Article
- Genetic characterization and pathogenicity in a mouse model of newly isolated bat-originated mammalian orthoreovirus in South Korea.Microbiology spectrum · 2024Article
- Investigating the etiologies of non-malarial febrile illness in Senegal using metagenomic sequencing.Nature communications · 2024Article
- Isolation and identification of a novel porcine-related recombinant mammalian orthoreovirus type 3 strain from cattle in Guangxi Province, China.Frontiers in microbiology · 2024Article
- The genomic characteristics and pathogenicity of a mammalian orthoreovirus within a new lineage from wild pika in plateau.Virologica Sinica · 2023Article
- Paired immunoglobulin-like receptor B is an entry receptor for mammalian orthoreovirus.Nature communications · 2023Article
- The Latest Cellular and Molecular Mechanisms of COVID-19 on Non-Lung Organs.Brain sciences · 2023Review
12 more citing papers are in PubMed but not listed here.
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Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
For many encephalitis cases, the cause remains unidentified. After 2 children (from the same family) received a diagnosis of acute necrotizing encephalopathy at Centre Hospitalier Universitaire (Tours, France), we attempted to identify the etiologic agent. Because clinical samples from the 2 patients were negative for all pathogens tested, urine and throat swab specimens were added to epithelial cells, and virus isolates detected were characterized by molecular analysis and electron microscopy. We identified a novel reovirus strain (serotype 2), MRV2Tou05, which seems to be closely related to porcine and human strains. A specific antibody response directed against this new reovirus strain was observed in convalescent-phase serum specimens from the patients, whereas no response was observed in 38 serum specimens from 38 healthy adults. This novel reovirus is a new etiologic agent of encephalitis.
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