Trial reportThe British journal of general practice : the journal of the Royal College of General Practitioners2011
Acupuncture for 'frequent attenders' with medically unexplained symptoms: a randomised controlled trial (CACTUS study).
Trial report in The British journal of general practice : the journal of the Royal College of General Practitioners, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 44 citations in OpenAlex.
- Behavioural modification interventions for medically unexplained symptoms in primary care: systematic reviews and economic evaluation.Health technology assessment (Winchester, England) · 2020Pooled it
- Quality of life, sense of coherence and experiences with three different treatments in patients with psychological distress in primary care: a mixed-methods study.BMC complementary and alternative medicine · 2015Trial
- Traditional acupuncture for people with medically unexplained symptoms: a longitudinal qualitative study of patients' experiences.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Trial
- Gap between the Scientificization and Utilization of Korean Medicine for Depressive Disorder in South Korea with the Highest Suicide Rate among OECD Countries.Journal of clinical medicine · 2022Article
- Whole Systems Research Methods in Health Care: A Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019Article
- Disease Prevention and Health Promotion: How Integrative Medicine Fits.American journal of preventive medicine · 2015Article
- Analysis and Thoughts about the Negative Results of International Clinical Trials on Acupuncture.Evidence-based complementary and alternative medicine : eCAM · 2015Review
- Comment on "Analysis and Thoughts about the Negative Results of International Clinical Trials on Acupuncture".Evidence-based complementary and alternative medicine : eCAM · 2015Article
- Psychological well-being of gynecologic and obstetric patients: a validation of the 12-item Well-Being Questionnaire (W-BQ12).Wiener klinische Wochenschrift · 2014Article
- Management of medically unexplained symptoms: outcomes of a specialist liaison clinic.Psychiatric bulletin (2014) · 2014Article
- Experiences of patients identifying with chronic Lyme disease in the healthcare system: a qualitative study.BMC family practice · 2014Article
- Patients with unexplained physical symptoms have poorer quality of life and higher costs than other patient groups: a cross-sectional study on burden.BMC health services research · 2013Article
- Methodological issues in pragmatic trials of complex interventions in primary care.The British journal of general practice : the journal of the Royal College of General Practitioners · 2012Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
- Acupuncture for 'frequent attenders' with medically unexplained symptoms.The British journal of general practice : the journal of the Royal College of General Practitioners · 2011Article
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMedically unexplained physical symptoms (MUPS) are common and difficult to treat.
aimTo investigate the effectiveness of adding five-element acupuncture to usual care in 'frequent attenders' with MUPS. DESIGN AND
settingRandomised controlled trial in four London general practices.
methodParticipants were 80 adults with MUPS, consulting GPs ≥8 times/year. The intervention was individualised five-element acupuncture, ≥12 sessions, immediately (acupuncture group) and after 26 weeks (control group). The primary outcome was 26-week Measure Yourself Medical Outcome Profile (MYMOP); secondary outcomes were wellbeing (W-BQ12), EQ-5D, and GP consultation rate. Intention-to-treat analysis was used, adjusting for baseline outcomes.
resultsParticipants (80% female, mean age 50 years, mixed ethnicity) had high health-resource use. Problems were 59% musculoskeletal; 65% >1 year duration. The 26-week questionnaire response rate was 89%. Compared to baseline, the mean 26-week MYMOP improved by 1.0 (95% confidence interval [CI] = 0.4 to 1.5) in the acupuncture group and 0.6 (95% CI = 0.3 to 0.9) in the control group (adjusted mean difference: acupuncture versus control -0.6 [95% CI = -1.1 to 0] P = 0.05). Other between-group adjusted mean differences were: W-BQ12 4.4 (95% CI = 1.6 to 7.2) P = 0.002; EQ-5D index 0.03 (95% CI = -0.11 to 0.16) P = 0.70; consultation rate ratio 0.90 (95% CI = 0.70 to 1.15) P = 0.4; and number of medications 0.56 (95% CI = 0.47 to 1.6) P = 0.28. All differences favoured the acupuncture group. Imputation for missing values reduced the MYMOP adjusted mean difference to -0.4 (95% CI = -0.9 to 0.1) P = 0.12. Improvements in MYMOP and W-BQ12 were maintained at 52 weeks.
conclusionThe addition of 12 sessions of five-element acupuncture to usual care resulted in improved health status and wellbeing that was sustained for 12 months.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.