ReviewRedox report : communications in free radical research2011
Unbalanced oxidant-antioxidant status and its effects in pediatric diseases.
Review in Redox report : communications in free radical research, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
14 citing papers in PubMed.
- Protopine-Enriched Dactylicapnos Scandens Root Fraction Improves Glucose Homeostasis in Cell and Mouse Models Via AMPK/PEPCK/G6Pase Modulation.Applied biochemistry and biotechnology · 2026Article
- Challenging directions in pediatric diabetes - the place of oxidative stress and antioxidants in systemic decline.Frontiers in pharmacology · 2024Review
- Evaluation of different bacterial honey isolates as probiotics and their efficient roles in cholesterol reduction.World journal of microbiology & biotechnology · 2022Article
- Antiviral Efficacy of Selected Natural Phytochemicals against SARS-CoV-2 Spike Glycoprotein Using Structure-Based Drug Designing.Molecules (Basel, Switzerland) · 2022Article
- Substituted Benzimidazole Analogues as Potential α-Amylase Inhibitors and Radical Scavengers.ACS omega · 2021Article
- Alterations of Extracellular Matrix Components in the Course of Juvenile Idiopathic Arthritis.Metabolites · 2021Review
- Isolation and characterization of novel acetylcholinesterase inhibitors fromRSC advances · 2020Article
- Phytochemical Analysis, Biochemical and Mineral Composition and GC-MS Profiling of Methanolic Extract of Chinese ArrowheadMolecules (Basel, Switzerland) · 2019Article
- Blood pressure from childhood to adolescence in obese youths in relation to insulin resistance and asymmetric dimethylarginine.Journal of endocrinological investigation · 2016Article
- Reactive oxygen species and serum antioxidant defense in juvenile idiopathic arthritis.Clinical rheumatology · 2015Article
- Obesity, hyperglycemia and endothelial function in inner city Bronx adolescents: a cross-sectional study.International journal of pediatric endocrinology · 2013Article
- Antioxidant activity of methanol extracts of different parts of Lantana camara.Asian Pacific journal of tropical biomedicine · 2012Article
- Relations between oxidized low-density lipoproteins and fat-soluble vitamin concentrations in obese children - preliminary study.Developmental period medicineArticle
- EVALUATION OF OXIDATIVE STRESS MARKERS IN GIRLS WITH PREMATURE THELARCHE AND PRECOCIOUS PUBERTY.Acta endocrinologica (Bucharest, Romania : 2005)Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Oxidative stress results from a disparity between the generation of reactive oxygen species and the antioxidant ability of the organism. The alteration of the oxidant-antioxidant system brings in adults an effective state of imbalance, which may influence the pathogenesis of many diseases. Oxidative stress also plays a pivotal role in the progression of various pathologies in childhood, through a manipulation of regulatory proteins. In fact, several studies have demonstrated that an unbalanced oxidant-antioxidant status is able to determine toxic effects even during infancy. Therefore, the aim of this review was to summarize current knowledge about the dynamic relationship between oxidative stress and systemic diseases during childhood. In order to better understand these complex mechanisms, a comprehensive review of the literature was done, focusing mainly on pre-pubertal children. In fact, this age-group offers a unique opportunity to exclude confounding factors, especially those related to the metabolic effects induced by puberty. Early identification of these very young patients should be aimed at minimizing the degree of oxidative damage. Only by achieving early diagnosis, will it be possible to identify those children who could benefit from specific therapeutic approaches targeting oxidative stress.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.