ArticleReproductive biology and endocrinology : RB&E2011
Establishment of an immortalized human endometrial stromal cell line with functional responses to ovarian stimuli.
Article in Reproductive biology and endocrinology : RB&E, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 27 citations in OpenAlex.
- Unlocking the Secrets of the Endometrium: Stem Cells, Niches and Modern Methodologies.Biomedicines · 2025Review
- The long road of drug development for endometriosis - Pains, gains, and hopes.Journal of controlled release : official journal of the Controlled Release Society · 2024Review
- The Essential Role of PGF2α/PTGFR in Molding Endometrial Breakdown and Vascular Dynamics, Regulated by HIF-1α in a Mouse Menstrual-like Model.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Strategies for modelling endometrial diseases.Nature reviews. Endocrinology · 2022Review
- The single-cell atlas of cultured human endometrial stromal cells.F&S science · 2022Article
- miR-21a inhibits decidual cell apoptosis by targeting Pdcd4.Genes & diseases · 2021Article
- Cigarette Smoke Extract Activates Hypoxia-Inducible Factors in a Reactive Oxygen Species-Dependent Manner in Stroma Cells from Human Endometrium.Antioxidants (Basel, Switzerland) · 2021Article
- The transcription factor HAND2 up-regulates transcription of theThe Journal of biological chemistry · 2020Article
- Identification of mRNAs related to endometrium function regulated by lncRNA CD36-005 in rat endometrial stromal cells.Reproductive biology and endocrinology : RB&E · 2018Article
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- Involvement of atypical transcription factor E2F8 in the polyploidization during mouse and human decidualization.Cell cycle (Georgetown, Tex.) · 2015Article
- Impact of 5-azacytidine on rat decidual cell proliferation.International journal of experimental pathology · 2014Article
- Mifepristone-exposured human endometrial endothelial cells in vitro.Reproductive sciences (Thousand Oaks, Calif.) · 2014Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studies on the mechanisms of decidualization and endometriosis are often hampered by lack of primary endometrial cells. To facilitate in vitro studies, we established a human endometrial stromal cell line, KC02-44D, immortalized with human telomerase reverse transcriptase. Upon exposure to ovarian stimuli, KC02-44D cells showed similar cytoskeletal marker or gene expression and biochemical phenotype to primary endometrial stromal cells. KC02-44D would be useful for studies of human endometrial function and its associated pathologies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.