Trial reportCurrent atherosclerosis reports2011
The high-risk plaque initiative: primary prevention of atherothrombotic events in the asymptomatic population.
Trial report in Current atherosclerosis reports, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 36 citations in OpenAlex.
- Association of cardiovascular health and risk prediction algorithms with subclinical atherosclerosis identified by carotid ultrasound.Cardiovascular digital health journal · 2023Article
- Systemic atherosclerotic plaque vulnerability in patients with Coronary Artery Disease with a single Whole Body FDG PET-CT scan.Asia Oceania journal of nuclear medicine & biology · 2020Article
- Ultrasound Molecular Imaging: Principles and Applications in Cardiovascular Medicine.Current cardiology reports · 2019Review
- Natural history of atherosclerotic disease progression as assessed by (18)F-FDG PET/CT.The international journal of cardiovascular imaging · 2016Article
- The Swedish CArdioPulmonary BioImage Study: objectives and design.Journal of internal medicine · 2015Observational
- Eyes on the Vulnerable.Maedica · 2015Article
- Pathophysiology of coronary artery disease leading to acute coronary syndromes.F1000prime reports · 2015Review
- Positron emission tomography of the vulnerable atherosclerotic plaque in man--a contemporary review.Clinical physiology and functional imaging · 2014Review
- Imaging subclinical atherosclerosis: is it ready for prime time? A review.Journal of cardiovascular translational research · 2014Review
- Nature or the natural evolution of plaque: what matters?Maedica · 2013Article
- Gadolinium-Based Contrast Agents for Vessel Wall Magnetic Resonance Imaging (MRI) of Atherosclerosis.Current cardiovascular imaging reports · 2013Article
- Spectral CT of carotid atherosclerotic plaque: comparison with histology.European radiology · 2012Article
- Coronary heart disease in young adults.Current atherosclerosis reports · 2012Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The High-Risk Plaque (HRP) Initiative is a research and development effort to advance the understanding, recognition, and management of asymptomatic individuals at risk for a near-term atherothrombotic event such as myocardial infarction or stroke. Clinical studies using the newest technologies have been initiated, including the BioImage Study in which novel approaches are tested in a typical health plan population. Asymptomatic at-risk individuals were enrolled, including a survey-only group (n = 865), a group undergoing traditional risk factor scoring (n = 718), and a group in which all were assessed for both risk factors and subclinical atherosclerosis (n = 6104). The latter two groups underwent baseline examination in a dedicated mobile facility equipped with advanced imaging tools suitable for noninvasive screening for subclinical atherosclerosis (coronary artery calcium by computed tomography [CT], carotid and aortic disease by ultrasound, and ankle-brachial index). Selected participants were offered advanced imaging (contrast-enhanced CT, magnetic resonance imaging, and positron emission tomography/CT). Plasma, PAXgene RNA, and DNA samples were obtained for biomarker discovery studies. All individuals will be followed until 600 major atherothrombotic events have occurred in those undergoing imaging.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.