Evidence map›Paper›PMID 21799695›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2011

Observed Changes in Risk during Naturopathic Treatment of Hypertension.

Ryan Bradley, Eva Kozura, Jennifer Kaltunas, Erica B Oberg, Jeffery Probstfield, Annette L Fitzpatrick

Open access · hybridAbstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 17 citations in OpenAlex.

  1. Naturopathic medicine for the prevention of cardiovascular disease: a randomized clinical trial.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2013
    Trial
  2. Trial
  3. Effects of oral glutathione supplementation on systemic oxidative stress biomarkers in human volunteers.Journal of alternative and complementary medicine (New York, N.Y.) · 2011
    Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. The State of the Evidence for Whole-System, Multi-Modality Naturopathic Medicine: A Systematic Scoping Review.Journal of alternative and complementary medicine (New York, N.Y.) · 2019
    Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ryan BradleyBastyr University, Kenmore, WA 98028, USA.
Eva Kozura
Jennifer Kaltunas
Erica B Oberg
Jeffery Probstfield
Annette L Fitzpatrick
Bastyr University · USUniversity of Washington · US

Funding

Institute for Translational Health Science (KL2)KL2RR025015 · NCRR · UNIVERSITY OF WASHINGTON · PI DISIS, MARY L. · 2007 to 2011
$9.3M
Building Research across Interdisciplinary Gaps (BRIDG) R90 Training Program - Administrative SupplementR90AT008924 · NCCIH · NATIONAL UNIVERSITY OF NATURAL MEDICINE · PI BRADLEY, RYAN D, ZWICKEY, HEATHER LEA · 2015 to 2025
$5.2M
NCCIH NIH HHS L30 AT004901NCCIH NIH HHS R90 AT008924NCRR NIH HHS KL2 RR025015
6 · The paper itself

Abstract

Few outcome assessments are published from complementary and alternative medicine (CAM) practices. We aimed to describe patient and practice characteristics of ND care for hypertension (HTN), quantify changes in blood pressure (BP), and evaluate the proportion achieving control of HTN during care. A retrospective, observational study of ND practice in HTN was performed in an outpatient clinic in WA State. Eighty-five charts were abstracted for the final analysis. At initiation of care, the mean patient age was 61 years, with 51% having stage 2 HTN, despite common use of anti-hypertensive medications (47%). Patients with both stage 1 and stage 2 HTN appeared to improve during care, with stage 2 patients achieving mean reductions of -26 mmHg (P < .0001) and -11 mmHg (P < .0001) in systolic BP (SBP) and diastolic BP (DBP), respectively. The proportion of patients achieving control (<140/90 mmHg) in both SBP and DBP was increased significantly from 14 to 44% (P < .033), although the statistical significance was not maintained upon correction for multiple comparisons. BP appears to improve during ND care for HTN, in a high-risk population. Randomized trials are warranted.

Identifiers

PMID21799695
PMCPMC3137652
OpenAlexW1966431423

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.