ArticleJournal of applied physiology (Bethesda, Md. : 1985)2011
The relationship between muscle deoxygenation and activation in different muscles of the quadriceps during cycle ramp exercise.
Article in Journal of applied physiology (Bethesda, Md. : 1985), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed.
- Trial
- Application of Molecular Hydrogen as an Antioxidant in Responses to Ventilatory and Ergogenic Adjustments during Incremental Exercise in Humans.Nutrients · 2021Trial
- The effect of dietary nitrate supplementation on the spatial heterogeneity of quadriceps deoxygenation during heavy-intensity cycling.Physiological reports · 2017Trial
- Muscle O2 extraction reserve during intense cycling is site-specific.Journal of applied physiology (Bethesda, Md. : 1985) · 2014Trial
- Characterizing the profile of muscle deoxygenation during ramp incremental exercise in young men.European journal of applied physiology · 2012Trial
- Increasing exercise intensity reduces heterogeneity of glucose uptake in human skeletal muscles.PloS one · 2012Trial
- Visually identified breakpoints in muscle oxygen saturation are not equivalent to ventilatory thresholds in national-level triathletes.European journal of applied physiology · 2026Article
- Effects of prior heavy exercise on deoxygenation in deep versus superficial muscle regions during subsequent heavy exercise in adult males.Physiological reports · 2026Article
- The overload loop: a distinct reoxygenation pattern above the second ventilatory threshold revealed by a new analytical method.Biology of sport · 2026Article
- Examination of neuromuscular and tissue oxygenation characteristics during submaximal treadmill running with blood flow restriction.European journal of applied physiology · 2026Article
- Simultaneous assessment of blood flow changes in femoral artery and skeletal muscle microvasculature using pulsed-wave and power Doppler ultrasonography.European journal of applied physiology · 2025Article
- Cardiac workload and skeletal muscle oxygenation during incremental exercise in healthy subjects.Physiological reports · 2025Article
- Continuous measurements of respiratory muscle blood flow and oxygen consumption using noninvasive frequency-domain near-infrared spectroscopy and diffuse correlation spectroscopy.Journal of applied physiology (Bethesda, Md. : 1985) · 2024Article
- Muscle reoxygenation is slower after higher cycling intensity, and is faster and more reliable in locomotor than in accessory muscle sites.Frontiers in physiology · 2024Article
- Single-distance and dual-slope frequency-domain near-infrared spectroscopy to assess skeletal muscle hemodynamics.Journal of biomedical optics · 2023Article
- Age-related difference in muscle metabolism patterns during upper limb's encircling exercise: a near-infrared spectroscopy study.Biomedical optics express · 2022Article
- Neuromuscular Fatigue Responses of Endurance- and Strength-Trained Athletes during Incremental Cycling Exercise.International journal of environmental research and public health · 2022Article
- Walking endurance, muscle oxygen extraction, and perceived fatigability after overground locomotor training in incomplete spinal cord injury: A pilot study.The journal of spinal cord medicine · 2022Article
- Influence of muscular contraction on vascular conductance during exercise above versus below critical power.Respiratory physiology & neurobiology · 2021Article
- Isolated finger flexor vs. exhaustive whole-body climbing tests? How to assess endurance in sport climbers?European journal of applied physiology · 2021Article
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Authors and funding
7 authors.
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Abstract
The relationship between muscle deoxygenation and activation was examined in three different muscles of the quadriceps during cycling ramp exercise. Seven young male adults (24 ± 3 yr; mean ± SD) pedaled at 60 rpm to exhaustion, with a work rate (WR) increase of 20 W/min. Pulmonary oxygen uptake was measured breath-by-breath, while muscle deoxygenation (HHb) and activity were measured by time-resolved near-infrared spectroscopy (NIRS) and surface electromyography (EMG), respectively, at the vastus lateralis (VL), rectus femoris (RF), and vastus medialis (VM). Muscle deoxygenation was corrected for adipose tissue thickness and normalized to the amplitude of the HHb response, while EMG signals were integrated (iEMG) and normalized to the maximum iEMG determined from maximal voluntary contractions. Muscle deoxygenation and activation were then plotted as a percentage of maximal work rate (%WR(max)). The HHb response for all three muscle groups was fitted by a sigmoid function, which was determined as the best fitting model. The c/d parameter for the sigmoid fit (representing the %WR(max) at 50% of the total amplitude of the HHb response) was similar between VL (47 ± 12% WR(max)) and VM (43 ± 11% WR(max)), yet greater (P < 0.05) for RF (65 ± 13% WR(max)), demonstrating a "right shift" of the HHb response compared with VL and VM. The iEMG also showed that muscle activation of the RF muscle was lower (P < 0.05) compared with VL and VM throughout the majority of the ramp exercise, which may explain the different HHb response in RF. Therefore, these data suggest that the sigmoid function can be used to model the HHb response in different muscles of the quadriceps; however, simultaneous measures of muscle activation are also needed for the HHb response to be properly interpreted during cycle ramp exercise.
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