ReviewTrends in biotechnology2012
Emerging technologies for point-of-care CD4 T-lymphocyte counting.
Review in Trends in biotechnology, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 1 synthesis or guideline pooled it.
- CD4Sensors (Basel, Switzerland) · 2026Pooled it
- Electrochemical microfluidic biosensor for the detection of CD4Microsystems & nanoengineering · 2025Article
- Microfluidic Assays for CD4 T Lymphocyte Counting: A Review.Biosensors · 2025Review
- Two-dimensional nanostructures based '-onics' and '-omics' in personalized medicine.Nanophotonics (Berlin, Germany) · 2022Review
- Microparticle-tagged image-based cell counting (ImmunoSpin) for CD4 + T cells.Mikrochimica acta · 2021Article
- Performance of the BD FACSPresto near to patient analyzer in comparison with representative conventional CD4 instruments in Cameroon.AIDS research and therapy · 2020Article
- An inkjet-printed polysaccharide matrix for on-chip sample preparation in point-of-care cell counting chambers.RSC advances · 2020Article
- A flow-through cell counting assay for point-of-care enumeration of CD4 T-cells.Journal of virological methods · 2019Article
- Article
- Point of Care Diagnostics for HIV in Resource Limited Settings: An Overview.Medicina (Kaunas, Lithuania) · 2018Review
- Biomarkers of Progression after HIV Acute/Early Infection: Nothing Compares to CD4⁺ T-cell Count?Viruses · 2018Article
- Magnetic Force-Based Microfluidic Techniques for Cellular and Tissue Bioengineering.Frontiers in bioengineering and biotechnology · 2018Review
- Near patient CD4 count in a hospitalized HIV patient population.Cytometry. Part B, Clinical cytometry · 2017Article
- Portable device for the detection of colorimetric assays.Royal Society open science · 2017Article
- Article
- A New Microfluidic Device for Classification of Microalgae Cells Based on Simultaneous Analysis of Chlorophyll Fluorescence, Side Light Scattering, Resistance Pulse Sensing.Micromachines · 2016Article
- Microfluidic differential immunocapture biochip for specific leukocyte counting.Nature protocols · 2016Article
- Article
- Assessing anti-malarial drug effects ex vivo using the haemozoin detection assay.Malaria journal · 2015Article
- Effectiveness of the credit-line approach for support of CD4 equipment functionality in northern Uganda.African journal of laboratory medicine · 2015Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
A CD4 T-lymphocyte count determines eligibility for antiretroviral therapy (ART) in patients recently diagnosed with HIV and also monitors the efficacy of ART treatment thereafter. ART slows the progression of HIV to AIDS. In the developing world, CD4 tests are often performed in centralized laboratories, typically in urban areas. The expansion of ART programs into rural areas has created a need for rapid CD4 counting because logistical barriers can delay the timely dissemination of test results and affect patient care through delay in intervention or loss of follow-up care. CD4 measurement at the point-of-care (POC) in rural areas could help the facilitation of ART and monitoring of treatment. This review highlights recent technology developments with applications towards determining CD4 counts at the POC.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.