ArticleParasites & vectors2011
Modelling the impact of vector control interventions on Anopheles gambiae population dynamics.
Article in Parasites & vectors, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 157 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
157 citing papers in PubMed, 3 syntheses or guidelines pooled it, 268 citations in OpenAlex.
- Inferring the epidemiological benefit of indoor vector control interventions against malaria from mosquito data.Nature communications · 2022Pooled it
- Mosquito feeding behavior and how it influences residual malaria transmission across Africa.Proceedings of the National Academy of Sciences of the United States of America · 2019Pooled it
- Systematic review of indoor residual spray efficacy and effectiveness against Plasmodium falciparum in Africa.Nature communications · 2018Pooled it
- Article
- From multiplicity of infection to force of infection in sparsely sampled high-transmissioneLife · 2026Article
- EliminatingInsects · 2026Article
- Beyond Temperature: Relative Humidity Systematically Shifts Juvenile Thermal Performance and Projected Population Growth in a Malaria Vector.Ecology letters · 2026Article
- Integrating mosquito genomics into simulation modeling: opportunities for better-informed biocontrol.Current opinion in insect science · 2026Review
- Article
- Estimating mosquito bionomics parameters with a hierarchical Bayesian model.Current research in parasitology & vector-borne diseases · 2026Article
- Integrating parallelCommunications health · 2026Article
- Article
- The spread of pyrethroid-resistant mosquitoes and their predicted malaria burden across the Democratic Republic of the Congo.Current research in parasitology & vector-borne diseases · 2026Article
- Prediction of mosquito vector abundance for three species in the Anopheles gambiae complex.Parasites & vectors · 2025Article
- Modelling the impact of different intervention packages for malaria control under varying intensities of pyrethroid resistance.Malaria journal · 2025Article
- Spatial modeling of the population dynamics of Anopheles mosquitoes in Madagascar.International journal of health geographics · 2025Article
- Climate change, urbanisation and transmission potential: Aedes aegypti mosquito projections forecast future arboviral disease hotspots in Brazil.PLoS neglected tropical diseases · 2025Article
- The dissemination potential of Microsporidia MB in Anopheles arabiensis mosquitoes is modulated by temperature.Scientific reports · 2025Article
- Modelling the effects of adult emergence on the surveillance and age distribution of medically important mosquitoes.PLoS computational biology · 2025Article
- Heterogeneous impacts for malaria control from larviciding across villages and considerations for monitoring and evaluation.PLoS pathogens · 2025Article
97 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundIntensive anti-malaria campaigns targeting the Anopheles population have demonstrated substantial reductions in adult mosquito density. Understanding the population dynamics of Anopheles mosquitoes throughout their whole lifecycle is important to assess the likely impact of vector control interventions alone and in combination as well as to aid the design of novel interventions.
methodsAn ecological model of Anopheles gambiae sensu lato populations incorporating a rainfall-dependent carrying capacity and density-dependent regulation of mosquito larvae in breeding sites is developed. The model is fitted to adult mosquito catch and rainfall data from 8 villages in the Garki District of Nigeria (the 'Garki Project') using Bayesian Markov Chain Monte Carlo methods and prior estimates of parameters derived from the literature. The model is used to compare the impact of vector control interventions directed against adult mosquito stages--long-lasting insecticide treated nets (LLIN), indoor residual spraying (IRS)-- and directed against aquatic mosquito stages, alone and in combination on adult mosquito density.
resultsA model in which density-dependent regulation occurs in the larval stages via a linear association between larval density and larval death rates provided a good fit to seasonal adult mosquito catches. The effective mosquito reproduction number in the presence of density-dependent regulation is dependent on seasonal rainfall patterns and peaks at the start of the rainy season. In addition to killing adult mosquitoes during the extrinsic incubation period, LLINs and IRS also result in less eggs being oviposited in breeding sites leading to further reductions in adult mosquito density. Combining interventions such as the application of larvicidal or pupacidal agents that target the aquatic stages of the mosquito lifecycle with LLINs or IRS can lead to substantial reductions in adult mosquito density.
conclusionsDensity-dependent regulation of anopheline larvae in breeding sites ensures robust, stable mosquito populations that can persist in the face of intensive vector control interventions. Selecting combinations of interventions that target different stages in the vector's lifecycle will result in maximum reductions in mosquito density.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.