ReviewHead & neck oncology2011
Exciting new advances in oral cancer diagnosis: avenues to early detection.
Review in Head & neck oncology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
67 citing papers in PubMed, 2 syntheses or guidelines pooled it, 199 citations in OpenAlex.
- Teledentistry: A Future Solution in the Diagnosis of Oral Lesions: Diagnostic Meta-Analysis and Systematic Review.Telemedicine journal and e-health : the official journal of the American Telemedicine Association · 2023Pooled it
- Non-invasive visual tools for diagnosis of oral cancer and dysplasia: A systematic review.Medicina oral, patologia oral y cirugia bucal · 2016Pooled it
- Automatic Oral Cancer Detection Using Improved Honey Badger Algorithm-Based Feature Selection.Diagnostics (Basel, Switzerland) · 2026Article
- INHBA-S100A16 dysregulation enables a non-invasive molecular stratification platform for rapid detection of oral squamous cell carcinoma: results from a large diagnostic case-control study.Biomarker research · 2026Article
- Article
- Evaluating the Role of VELscope in Oral Cancer and Pre-Cancer Screening: A Scoping Review.Asian Pacific journal of cancer prevention : APJCP · 2026Article
- Resveratrol in Oral Squamous Cell Carcinoma: Preclinical Evidence and Translational Opportunities.Oncology research · 2026Review
- Characterizing volatile organic compound profiles in oral cancer using multiple sample collection approaches by GC-IMS and TD-GC-MS.Scientific reports · 2025Article
- Use of Oral Rub and Rinse Technique for Oral Cancer Screening: Results from a Community-based Program in an LMIC.Asian Pacific journal of cancer prevention : APJCP · 2025Article
- Clinico-pathological specificities of gingival carcinoma among 32 patients with oral cancer: a cross sectional retrospective and observational study.BMC oral health · 2024Observational
- Longitudinal Study of Oral Precancerous Lesions: Transformation Rate and Predictive Markers for Malignancy.Journal of pharmacy & bioallied sciences · 2024Article
- Nano-modified screen-printed electrode-based electrochemical immunosensors for oral cancer biomarker detection in undiluted human serum and saliva samples.Nanoscale advances · 2024Article
- U-shaped fusion convolutional transformer based workflow for fast optical coherence tomography angiography generation in lips.Biomedical optics express · 2023Article
- Serum and Saliva LDH Levels in Patients with Habit, Oral Potentially Malignant Disorders (OPMDs), and Oral Squamous Cell Carcinoma (OSCC): A Spectrophotometry Study.Journal of pharmacy & bioallied sciences · 2023Article
- Diagnosis of Oral Cancers by Targeting VPAC Receptors: Preliminary Report.Asian Pacific journal of cancer prevention : APJCP · 2023Article
- Current advances in noninvasive methods for the diagnosis of oral squamous cell carcinoma: a review.European journal of medical research · 2023Review
- Article
- Article
- Adjunctive Techniques and Diagnostic Aids in the Early Detection of Oral Premalignant Disorders and Cancer: An Update for the General Dental Practitioners.Journal of pharmacy & bioallied sciences · 2022Review
- Improving the Diagnostic Performance by Adding Methylation Marker to Conventional Visual Examination in Identifying Oral Cancer.Diagnostics (Basel, Switzerland) · 2022Article
7 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The prognosis for patients with oral squamous cell carcinoma remains poor in spite of advances in therapy of many other malignancies. Early diagnosis and treatment remains the key to improved patient survival. Because the scalpel biopsy for diagnosis is invasive and has potential morbidity, it is reserved for evaluating highly suspicious lesions and not for the majority of oral lesions which are clinically not suspicious. Furthermore, scalpel biopsy has significant interobserver and intraobserver variability in the histologic diagnosis of dysplasia. There is an urgent need to devise critical diagnostic tools for early detection of oral dysplasia and malignancy that are practical, noninvasive and can be easily performed in an out-patient set-up. Diagnostic tests for early detection include brush biopsy, toluidine blue staining, autofluorescence, salivary proteomics, DNA analysis, biomarkers and spectroscopy. This state of the art review critically examines these tests and assesses their value in identifying oral squamous cell carcinoma and its precursor lesions.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.