ArticleHeadache
Trimester-specific blood pressure levels and hypertensive disorders among pregnant migraineurs.
Article in Headache. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 31 citations in OpenAlex.
- Association between migraine, migraine subtype, and adverse pregnancy outcomes: A systematic review and meta-analysis.Acta obstetricia et gynecologica Scandinavica · 2025Pooled it
- Headache and pregnancy: a systematic review.The journal of headache and pain · 2017Pooled it
- Safety and Effectiveness of Pain Medications for Migraine Management During Pregnancy and Lactation.Paediatric drugs · 2026Review
- Review
- Article
- The Potential Protective Role of Aspirin Against Migraine in Pregnant Women.Medical science monitor : international medical journal of experimental and clinical research · 2020Review
- Migraine during pregnancy and in the puerperium.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2019Review
- Patterns and predictors of analgesic use in pregnancy: a longitudinal drug utilization study with special focus on women with migraine.BMC pregnancy and childbirth · 2017Article
- Pharmacological treatment of migraine during pregnancy and breastfeeding.Nature reviews. Neurology · 2015Review
- Depression, anxiety and stress among pregnant migraineurs in a pacific-northwest cohort.Journal of affective disorders · 2015Article
- Lifetime prevalence and correlates of migraine among women in a pacific northwest pregnancy cohort study.Headache · 2014Article
- Agreement of self-reported physician diagnosis of migraine with international classification of headache disorders-II migraine diagnostic criteria in a cross-sectional study of pregnant women.BMC women's health · 2013Article
- Triptan safety during pregnancy: a Norwegian population registry study.European journal of epidemiology · 2013Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 1 country.
Funding
Abstract
objectiveWe evaluated the influence of physician-diagnosed migraine on blood pressure levels and the risk of hypertensive disorders of pregnancy in a clinic-based prospective cohort study of 3373 healthy pregnant women.
backgroundThe relationship between migraine and blood pressure is controversial with results from several studies suggesting positive associations, while others suggest null or inverse associations. To our knowledge, no previous study has investigated blood pressure profiles among pregnant migraineurs.
methodsWe abstracted blood pressure values and delivery information from medical records of women presenting to prenatal clinics in Washington State. Mean blood pressure differences for pregnant migraineurs and non-migraineurs were estimated in regression models, using generalized estimating equations. We calculated odds ratios and 95% confidence intervals (95% CIs) for gestational hypertension and preeclampsia in relation to migraine status.
resultsMean first, second, and third trimester systolic blood pressures (SBP) were elevated among pregnant migraineurs as compared with non-migraineurs. Migraineurs had higher mean third trimester SBP (4.08 mmHg) than non-migraineurs. Trimester-specific diastolic blood pressure (DBP) values were variably related with migraine status. Mean first (0.82 mmHg) and third (2.39 mmHg) trimester DBP were higher, and second trimester DBP values were lower (-0.24) among migraineurs as compared with non-migraineurs. Migraineurs had a 1.53-fold increased odds of preeclampsia (95% CI 1.09 to 2.16). Additionally, migraineurs who were overweight or obese had a 6.10-fold increased odds of preeclampsia (95% CI 3.83 to 9.75) as compared with lean non-migraineurs.
conclusionsPregnant migraineurs had elevated blood pressures, particularly SBP measured in the third trimester, and a higher risk of preeclampsia than pregnant women without migraine. Observed associations were more pronounced among overweight or obese migraineurs. Our findings add to the accumulating evidence of adverse pregnancy outcomes among migraineurs.
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