ArticleClinical autonomic research : official journal of the Clinical Autonomic Research Society2011
Fludrocortisone improves nausea in children with orthostatic intolerance (OI).
Article in Clinical autonomic research : official journal of the Clinical Autonomic Research Society, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 32 citations in OpenAlex.
- Use of an allostatic neurotechnology by adolescents with postural orthostatic tachycardia syndrome (POTS) is associated with improvements in heart rate variability and changes in temporal lobe electrical activity.Experimental brain research · 2016Trial
- Rome V Pediatric Upper Gastrointestinal Disorders of Gut-Brain Interaction.Gastroenterology · 2026Review
- Risk Factors for Transition of Care in Disorders of Gut-Brain Interaction: A Narrative Review and Expert Opinion.Children (Basel, Switzerland) · 2025Review
- Functional Nausea Is Real and Makes You Sick.Frontiers in pediatrics · 2022Review
- Chronic nausea and orthostatic intolerance: Diagnostic utility of orthostatic challenge duration, Nausea Profile Questionnaire, and neurohumoral measures.Neurogastroenterology and motility · 2018Article
- Distinct neurohumoral biomarker profiles in children with hemodynamically defined orthostatic intolerance may predict treatment options.American journal of physiology. Heart and circulatory physiology · 2016Article
- Relationship among nausea, anxiety, and orthostatic symptoms in pediatric patients with chronic unexplained nausea.Experimental brain research · 2014Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledINTRODUCTION/
resultsIn 17 patients, chronic idiopathic nausea was associated with orthostatic intolerance (OI) by abnormal tilt table tests (88%) or gastric dysrhythmias (71%). After fludrocortisone treatment, there was >26% nausea improvement in 71%, 1-25% in 6%, and no improvement in 24%. In six subjects, EGGs repeated after >50% nausea improvement all remained to be abnormal, suggesting nausea is independent of gastric dysrhythmias.
conclusionAssociation of EGG abnormalities and OI in this subset of nausea patients suggests a generalized disturbance of autonomic regulation.
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Registered trials
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