ReviewInternational journal of nanomedicine2011
Application of supercritical antisolvent method in drug encapsulation: a review.
Review in International journal of nanomedicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Development of Balangu seed mucilage nanoparticles fabricated through ultrasonication-antisolvent method for encapsulation of gallic acid.Scientific reports · 2025Article
- Degradation Kinetic Studies of BSA@ZIF-8 Nanoparticles with Various Zinc Precursors, Metal-to-Ligand Ratios, and pH Conditions.ACS omega · 2023Article
- Encapsulation: A Strategy to Deliver Therapeutics and Bioactive Compounds?Pharmaceuticals (Basel, Switzerland) · 2023Review
- Generation of Highly Antioxidant Submicron Particles fromAntioxidants (Basel, Switzerland) · 2023Article
- Supercritical Fluid Technologies for the Incorporation of Synthetic and Natural Active Compounds into Materials for Drug Formulation and Delivery.Pharmaceutics · 2022Review
- Promising Natural Products in New Drug Design, Development, and Therapy for Skin Disorders: An Overview of Scientific Evidence and Understanding Their Mechanism of Action.Drug design, development and therapy · 2022Review
- Solid Dosage Forms of Biopharmaceuticals in Drug Delivery Systems Using Sustainable Strategies.Molecules (Basel, Switzerland) · 2021Review
- Applications of Supercritical Anti-Solvent Process in Preparation of Solid Multicomponent Systems.Pharmaceutics · 2021Review
- PLA/PLGA-Based Drug Delivery Systems Produced with Supercritical COPharmaceutics · 2020Review
- Preparation, Characterization, and In Vitro Sustained Release Profile of Resveratrol-Loaded Silica Aerogel.Molecules (Basel, Switzerland) · 2020Article
- Using Supercritical Fluid Technology as a Green Alternative During the Preparation of Drug Delivery Systems.Pharmaceutics · 2019Review
- Microencapsulation and Nanoencapsulation Using Supercritical Fluid (SCF) Techniques.Pharmaceutics · 2019Review
- Solution-enhanced dispersion by supercritical fluids: an ecofriendly nanonization approach for processing biomaterials and pharmaceutical compounds.International journal of nanomedicine · 2018Review
- Acoustically enhanced microfluidic mixer to synthesize highly uniform nanodrugs without the addition of stabilizers.International journal of nanomedicine · 2018Article
- Supercritical Fluid Technology: An Emphasis on Drug Delivery and Related Biomedical Applications.Advanced healthcare materials · 2017Review
- Formation of curcumin nanoparticles via solution-enhanced dispersion by supercritical CO2.International journal of nanomedicine · 2015Article
- Nanotechnology: an effective tool for enhancing bioavailability and bioactivity of phytomedicine.Asian Pacific journal of tropical biomedicine · 2014Review
- Effect of supercritical fluid density on nanoencapsulated drug particle size using the supercritical antisolvent method.International journal of nanomedicine · 2012Article
- Formation of methotrexate-PLLA-PEG-PLLA composite microspheres by microencapsulation through a process of suspension-enhanced dispersion by supercritical CO2.International journal of nanomedicine · 2012Article
- A novel preparation method for 5-aminosalicylic acid loaded Eudragit S100 nanoparticles.International journal of molecular sciences · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The review focuses on the application of supercritical fluids as antisolvents in the pharmaceutical field and demonstrates the supercritical antisolvent method in the use of drug encapsulation. The main factors for choosing the solvent and biodegradable polymer to produce fine particles to ensure effective drug delivery are emphasized and the effect of polymer structure on drug encapsulation is illustrated. The review also demonstrates the drug release mechanism and polymeric controlled release system, and discusses the effects of the various conditions in the process, such as pressure, temperature, concentration, chemical compositions (organic solvents, drug, and biodegradable polymer), nozzle geometry, CO(2) flow rate, and the liquid phase flow rate on particle size and its distribution.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.