Evidence map›Paper›PMID 21795784›Full record

ArticleActa crystallographica. Section F, Structural biology and crystallization communications2011

Structures of the rat complement regulator CrrY.

Pietro Roversi, Steven Johnson, Joseph J E Caesar, Florence McLean, Kirstin J Leath, Stefanos A Tsiftsoglou, B Paul Morgan, Claire L Harris, Robert B Sim, Susan M Lea

Open access · hybridAbstract read
In one paragraph

Article in Acta crystallographica. Section F, Structural biology and crystallization communications, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Structural basis for complement factor I control and its disease-associated sequence polymorphisms.Proceedings of the National Academy of Sciences of the United States of America · 2011
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Pietro RoversiSir William Dunn School of Pathology, Oxford University, South Parks Road, Oxford OX4 3RE, England.
Steven Johnson
Joseph J E Caesar
Florence McLean
Kirstin J Leath
Stefanos A Tsiftsoglou
B Paul Morgan
Claire L Harris
Robert B Sim
Susan M Lea
University of Oxford · GBCardiff University · GB

Funding

Medical Research Council G0400775Medical Research Council G0400775(71657)Wellcome Trust 083599
6 · The paper itself

Abstract

Complement receptor 1-related protein Y (CrrY) is an important cell-surface regulator of complement that is unique to rodent species. The structure of rat CrrY domains 1-4 has been determined in two distinct crystal forms and reveals a 70° bend between domains 3 and 4. Comparisons of this structure with those of other complement regulators suggests that rearrangement of this interface may occur on forming the regulatory complex with C3b.

Indexed as

AnimalsAntigens, SurfaceCrystallography, X-RayHumansModels, MolecularProtein Structure, TertiaryRatsReceptors, Cell SurfaceStructural Homology, ProteinAntigens, SurfaceCr1l protein, ratReceptors, Cell Surface

Identifiers

PMID21795784
PMCPMC3144786
OpenAlexW2074955991

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.