ArticleScience translational medicine2011
Antibody repertoire: embracing diversity.
Article in Science translational medicine, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Significant Impact of Immunogen Design on the Diversity of Antibodies Generated by Carbohydrate-Based Anticancer Vaccine.ACS chemical biology · 2015Article
- Coadministration of seasonal influenza vaccine and MVA-NP+M1 simultaneously achieves potent humoral and cell-mediated responses.Molecular therapy : the journal of the American Society of Gene Therapy · 2014Article
- Modulation of SAP dependent T:B cell interactions as a strategy to improve vaccination.Current opinion in virology · 2013Review
- Antigenic drift of the pandemic 2009 A(H1N1) influenza virus in A ferret model.PLoS pathogens · 2013Article
Corrections and comments
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Authors and funding
2 authors.
Funding
Abstract
In this Perspective, we discuss two papers that show that the breadth of the antibody response to vaccines could be manipulated by the use of particular vaccine adjuvants that stimulate innate immune mechanisms. The ability to increase the repertoire of antibodies induced by a vaccine may help to control variable pathogens that alter their exposed antigens to evade the immune system.
Indexed as
Identifiers
21795586What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.