Evidence map›Paper›PMID 21795512›Full record

ArticleJournal of clinical microbiology2011

Sensitivity and specificity of immunocytochemical staining of mycobacterial antigens in the cytoplasm of cerebrospinal fluid macrophages for diagnosing tuberculous meningitis.

Yuquan Shao, Ping Xia, Tao Zhu, Jiong Zhou, Yuan Yuan, Hao Zhang, Jianjun Chen, Xingyue Hu

Open access · hybridAbstract readEvaluation Study
In one paragraph

Article in Journal of clinical microbiology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 5 institutions in 1 country.

Yuquan ShaoDepartment of Neurology, Affiliated Sir Run Run Shaw Hospital, 3 East Qingchun Road, Hangzhou 310016, Zhejiang, China.
Ping Xia
Tao Zhu
Jiong Zhou
Yuan Yuan
Hao Zhang
Jianjun Chen
Xingyue Hu
Zhejiang University · CNSir Run Run Shaw Hospital · CNHangzhou First People's Hospital · CNLishui City People's Hospital · CNSecond Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The sensitivity and specificity of immunocytochemical staining of mycobacterial antigens in the cytoplasm of cerebrospinal fluid (CSF) macrophages for diagnosis of tuberculous meningitis (TBM) was prospectively compared with Ahuja criteria from 393 consecutive CSF specimens. The assay can play an important role for the diagnosis of TBM, with sensitivity of 73.5% and specificity of 90.7%.

Indexed as

AdolescentAdultAgedAged, 80 and overAntigens, BacterialCerebrospinal FluidChildChild, PreschoolClinical Laboratory TechniquesFemaleHumansImmunohistochemistryInfantMacrophagesMaleMiddle AgedAntigens, Bacterial

Identifiers

PMID21795512
PMCPMC3165579
OpenAlexW2167276265

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.