Evidence map›Paper›PMID 21795475›Full record

ArticleThe Journal of general virology2011

Discovery of an orthoreovirus in the aborted fetus of a Steller sea lion (Eumetopias jubatus).

Gustavo Palacios, James F X Wellehan, Stephen Raverty, Ana V Bussetti, Jeffrey Hui, Nazir Savji, Hendrik H Nollens, Dyanna Lambourn, Christopher Celone, Stephen Hutchison and 3 more

Open access · greenAbstract read
In one paragraph

Article in The Journal of general virology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Viral metagenomic survey of Caspian seals.Frontiers in veterinary science · 2024
    Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 2 countries.

Gustavo PalaciosCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
James F X WellehanMarine Animal Disease Laboratory, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Stephen RavertyAnimal Health Center, Abbotsford Agriculture Centre, Provincial Government of British Columbia, Abbotsford, British Columbia, Canada.
Ana V BussettiCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Jeffrey HuiCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Nazir SavjiCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Hendrik H NollensMarine Animal Disease Laboratory, College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.
Dyanna LambournMarine Mammal Investigations, Washington Department of Fish and Wildlife, Washington, USA.
Christopher Celone454 Life Sciences, Branford, CT, USA.
Stephen Hutchison454 Life Sciences, Branford, CT, USA.
Charles H CalisherArthropod-borne and Infectious Diseases Laboratory, Department of Microbiology, Immunology and Pathology, College of Veterinary Medicine and Biomedical Sciences, Colorado State University, Fort Collins, CO, USA.
Ole NielsenDepartment of Fisheries and Oceans Canada, Winnipeg, Manitoba, Canada.
W Ian LipkinCenter for Infection and Immunity, Mailman School of Public Health, Columbia University, New York, NY, USA.
Columbia University · USEnzo Life Sciences (United States) · USUniversity of Florida · USColorado State University · USFisheries and Oceans Canada · CAGovernment of British Columbia · CAWashington Department of Fish and Wildlife · US

Funding

Viral Pathogenesis and TherapeuticsU54AI057158 · NIAID · WADSWORTH CENTER · PI LEVY, DAVID E · 2003 to 2014
$100.8M
A Staged Strategy for Virus Identification and DiscoveryR01AI051292 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI LIPKIN, W. IAN · 2002 to 2005
$2.0M
World Reference Center for ArbovirusesN01AI30027 · NIAID · UNIVERSITY OF TEXAS MED BR GALVESTON · PI TESH, ROBERT · 2008 to 2012
$746k
NIAID NIH HHS AI051292NIAID NIH HHS N01 AI030027NIAID NIH HHS N01 AI30027NIAID NIH HHS R01 AI051292NIAID NIH HHS U54 AI057158NIAID NIH HHS U54 AI57158
6 · The paper itself

Abstract

An aborted mid-gestational male Steller sea lion fetus with an attached placenta was recovered on the floor of an open floating capture trap located off Norris Rock near Denman Island, British Columbia. Viral culture of the placenta demonstrated cytopathic effect. Although no specific signal was obtained in microarray experiments using RNA obtained from viral culture, elution and sequence analysis revealed the presence of a reovirus. Complete genome pyrosequencing led to the identification of an orthoreovirus that we have tentatively named Steller sea lion reovirus (SSRV). Phylogenetic analysis revealed similarities between SSRV and orthoreoviruses of birds, bats and other mammals that suggests potential for interspecies transmission.

Indexed as

Genome, ViralAborted FetusAnimalsBritish ColumbiaCluster AnalysisFemaleMaleMolecular Sequence DataOrthoreovirusPhylogenyPlacentaPregnancyRNA, ViralSea LionsSequence Analysis, DNARNA, Viral

Identifiers

PMID21795475
PMCPMC3352366
OpenAlexW2105634371

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.