Trial reportFertility and sterility2011
Comparing focused ultrasound and uterine artery embolization for uterine fibroids-rationale and design of the Fibroid Interventions: reducing symptoms today and tomorrow (FIRSTT) trial.
Trial report in Fertility and sterility, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00995878 (The FIRSTT Study), which is not on this map. Cited by 13 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The FIRSTT Study: Comparing Focused Ultrasound and Uterine Artery Embolization for Uterine Fibroids
Who cites it
13 citing papers in PubMed, 46 citations in OpenAlex.
- Uterine and Fibroid Imaging Analysis from the FIRSTT Study.Journal of women's health (2002) · 2022Trial
- FIRSTT study: randomized controlled trial of uterine artery embolization vs focused ultrasound surgery.American journal of obstetrics and gynecology · 2019Trial
- Periprocedural outcomes comparing fibroid embolization and focused ultrasound: a randomized controlled trial and comprehensive cohort analysis.American journal of obstetrics and gynecology · 2017Trial
- Fibroid interventions: reducing symptoms today and tomorrow: extending generalizability by using a comprehensive cohort design with a randomized controlled trial.American journal of obstetrics and gynecology · 2016Trial
- Uterine artery embolization, surgery and high intensity focused ultrasound in the treatment of uterine fibroids: a network meta-analysis.Quantitative imaging in medicine and surgery · 2021Article
- The influence of uterine artery embolisation on ovarian reserve, fertility, and pregnancy outcomes - a review of literature.Przeglad menopauzalny = Menopause review · 2016Review
- Effect of menses on standardized assessment of sexual dysfunction among women with uterine fibroids: a cohort study.Fertility and sterility · 2015Article
- Stro-1/CD44 as putative human myometrial and fibroid stem cell markers.Fertility and sterility · 2015Article
- Magnetic Resonance-Guided High-Intensity Focused Ultrasound (MRgHIFU) Treatment of Symptomatic Uterine Fibroids: An Evidence-Based Analysis.Ontario health technology assessment series · 2015Review
- Cost comparison between uterine-sparing fibroid treatments one year following treatment.Journal of therapeutic ultrasound · 2014Article
- The burden of uterine fibroids for African-American women: results of a national survey.Journal of women's health (2002) · 2013Article
- Treatment for Uterine Fibroids: Searching for Effective Drug Therapies.Drug discovery today. Therapeutic strategies · 2012Article
- Proceedings from the Third National Institutes of Health International Congress on Advances in Uterine Leiomyoma Research: comprehensive review, conference summary and future recommendations.Human reproduction updateArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
Abstract
objectiveTo present the rationale, design, and methodology of the Fibroid Interventions: Reducing Symptoms Today and Tomorrow (FIRSTT) study.
designRandomized clinical trial.
settingTwo academic medical centers. PATIENT(S): Premenopausal women with symptomatic uterine fibroids. INTERVENTION(S): Participants are randomized to two U.S. Food and Drug Administration-approved minimally invasive treatments for uterine leiomyomas: uterine artery embolization and magnetic resonance-guided focused ultrasound. MAIN OUTCOME MEASURE(S): The primary endpoint is defined as the need for an additional intervention for fibroid symptoms following treatment. Secondary outcomes consist of group differences in symptom alleviation, recovery trajectory, health-related quality of life, impairment of ovarian reserve, treatment complications, and the economic impact of these issues. RESULT(S): The trial is currently in the phase of active recruitment. CONCLUSION(S): This randomized clinical trial will provide important evidence-based information for patients and health care providers regarding optimal minimally invasive treatment approach for women with symptomatic uterine leiomyomas. CLINICAL
trial registrationNCT00995878.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.