Evidence map›Paper›PMID 21793958›Full record

Trial reportAddiction (Abingdon, England)2011

Effects of a randomized contingency management intervention on opiate abstinence and retention in methadone maintenance treatment in China.

Yih-Ing Hser, Jianhua Li, Haifeng Jiang, Ruimin Zhang, Jiang Du, Congbin Zhang, Bo Zhang, Elizabeth Evans, Fei Wu, Yen-Jung Chang and 5 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Addiction (Abingdon, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04706624 (Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics), which is not on this map. Cited by 50 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 13 pooled it
4.8field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04706624 nacompletednot on this mapstarted 2021, after this paper: background citation

Screen, Treat and Retain Meth-using People With Opioid Use Disorders at Methadone Clinics

TypeinterventionalSponsorHanoi Medical UniversityRan2021 to 2025Enrolled667ConditionsMethamphetamine Abuse, Opioid-use Disorder, HIV SeropositivityArmsContingency management (12 weeks), Contingency management (6 weeks), SMS reminders, Matrix only, Matrix + Contingency management
3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 13 syntheses or guidelines pooled it, 78 citations in OpenAlex.

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  8. Pharmacological interventions for drug-using offenders.The Cochrane database of systematic reviews · 2015
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  19. Voucher incentives improve linkage to and retention in care among HIV-infected drug users in Chennai, India.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2014
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 2 countries.

Yih-Ing HserUniversity of California, Los Angeles, CA 90025, USA. yhser@ucla.edu
Jianhua Li
Haifeng Jiang
Ruimin Zhang
Jiang Du
Congbin Zhang
Bo Zhang
Elizabeth Evans
Fei Wu
Yen-Jung Chang
Chinyi Peng
David Huang
Maxine L Stitzer
John Roll
Min Zhao
University of California, Los Angeles · USYunnan Institute For Drug Abuse · CNShanghai Mental Health Center · CNJohns Hopkins University · USShanghai Jiao Tong University · CNUCLA Health · USWashington State University · US

Funding

STATISTICAL SUPPORT/DATA MANAGEMENT COREP30DA016383 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSER, YIH-ING · 2005 to 2015
$8.6M
Drug Abuse: Epidemiology, Treatment Process, & OutcomesK05DA017648 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSER, YIH-ING · 2008 to 2012
$569k
Reducing HIV/AIDS and Drug Abuse: Linking Compulsory Rehabilitation to Methadone R21DA025385 · NIDA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HSER, YIH-ING · 2008 to 2008
$121k
NIDA NIH HHS K05 DA017648NIDA NIH HHS K05DA017648NIDA NIH HHS P30 DA016383NIDA NIH HHS P30DA016383NIDA NIH HHS R21 DA025385NIDA NIH HHS R21DA025385
6 · The paper itself

Abstract

aimsMethadone maintenance treatment has been made available in China in response to the rapid spread of human immunodeficiency virus (HIV), but high rates of dropout and relapse are problematic. The aim of this study was to apply and test if a contingency management (or motivational incentives) intervention can improve treatment retention and reduce drug use.

designRandom assignment to usual care with (n = 160) or without (n = 159) incentives during a 12-week trial. Incentives participants earned draws for a chance to win prizes on two separate tracks targeting opiate-negative urine sample or consecutive attendance; the number of draws increased with continuous abstinence or attendance.

settingCommunity-based methadone maintenance clinics in Shanghai and Kunming.

participantsThe sample was 23.8% female, mean age was 38, mean years of drug use was 9.4 and 57.8% had injected drugs in the past 30 days. MEASUREMENTS: Treatment retention and negative drug urine.

findingsRelative to the treatment-as-usual (control) group, better retention was observed among the incentive group in Kunming (75% versus 44%), but no difference was found in Shanghai (90% versus 86%). Submission of negative urine samples was more common among the incentive group than the usual care (74% versus 68% in Shanghai, 27% versus 18% in Kunming), as was the longest duration of sustained abstinence (7.7 weeks versus 6.5 in Shanghai, 2.5 versus 1.6 in Kunming). The average total prize amount was 371 Yuan (or $55) per participant (527 for Shanghai versus 216 in Kunming).

conclusionsContingency management improves treatment retention and drug abstinence in methadone maintenance treatment clinics in China, although there can be considerable site differences in magnitude of effects.

Indexed as

AdultAnalysis of VarianceChinaFemaleHIV InfectionsHumansMaleMethadoneNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPatient CompliancePatient DropoutsRecurrenceRewardSubstance Abuse, IntravenousMethadoneNarcotic Antagonists

Identifiers

PMID21793958
PMCPMC3174353
OpenAlexW1714487263

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.