ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2012
Asthma-like symptoms in the first year of life and health-related quality of life at age 12 months: the Generation R study.
Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The severity of acute bronchiolitis in infants was associated with quality of life nine months later.Acta paediatrica (Oslo, Norway : 1992) · 2016Trial
- Article
- Infant feeding and health-related quality of life in healthy Chinese infants: results from a prospective, observational cohort study.Health and quality of life outcomes · 2016Observational
- Exposure to traumatic events and health-related quality of life in preschool-aged children.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2013Article
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10 authors.
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Abstract
purposeThis study compares HRQOL among subgroups of infants with asthma-like symptoms to a subgroup without such symptoms and examines independent associations between asthma-like symptoms during the first year of life and HRQOL at age 12 months.
methodsOur study sample included 5,000 infants participating in the Generation R study. Their parents completed structured questionnaires to obtain information on asthma-like symptoms, HRQOL, infants', and maternal characteristics. Asthma-like symptoms were defined according to the number of positive answers to 12 items on lower respiratory symptoms. HRQOL was measured using the ITQOL. Higher scores indicated better HRQOL.
resultsInfants with asthma-like symptoms had significantly lower HRQOL scores for all ITQOL scales. Among the subgroup with severe symptoms (4% of the infants), relevant deficits in HRQOL were observed for most ITQOL scales, particularly for General Health, Bodily Pain, and Family Activities (effect sizes ≥ 0.8). In multivariate linear models, asthma-like symptoms were independently associated with 6 ITQOL scales. The population attributable risks were especially high for Family Activities, General Health, Parental Emotional, and Parental Time.
conclusionsAsthma-like symptoms during the first year of life are associated with impaired quality of life at age 12 months. At population level, asthma-like symptoms were associated with lower HRQOL, regardless of symptom severity.
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