ArticleJournal of assisted reproduction and genetics2011
Should ICSI be recommended routinely in patients with four or fewer oocytes retrieved?
Article in Journal of assisted reproduction and genetics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03370068 (The Role of Intracytoplasmic Sperm Injection in Non-male Factor Infertility in Maternal Age Above 39), which is not on this map. Cited by 25 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Role of Intracytoplasmic Sperm Injection in Non-male Factor Infertility in Maternal Age Above 39
Who cites it
25 citing papers in PubMed.
- Trial
- Indications for Micro-Injection of Sperm in Assisted Reproduction: A Consensus Statement.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Trends in the Use and Indications for Intracytoplasmic Sperm Injection Between 2005 and 2017: A State-Wide Descriptive Cohort Analysis.The Australian & New Zealand journal of obstetrics & gynaecology · 2026Article
- Intracytoplasmic sperm injection hampers fertilization rate and pregnancy per initiated cycle in patients with extremely poor ovarian response.Archives of gynecology and obstetrics · 2025Article
- Secretomes from Conventional Insemination and Intra-Cytoplasmic Sperm Injection Derived Embryos Differentially Modulate Endometrial Cells In Vitro.Reproductive sciences (Thousand Oaks, Calif.) · 2024Article
- Article
- Good practice recommendations on add-ons in reproductive medicine†.Human reproduction (Oxford, England) · 2023Article
- Opportunities and Limits of Conventional IVF versus ICSI: It Is Time to Come off the Fence.Journal of clinical medicine · 2022Review
- Physical activity and sperm quality: influence in sperm donors.Reproductive biology and endocrinology : RB&E · 2022Article
- Impact of intracytoplasmic sperm injection in women with non-male factor infertility: A systematic review and meta-analysis.Frontiers in reproductive health · 2022Review
- Article
- Comparison of in vitro fertilisation/intracytoplasmic sperm injection on live birth rates in couples with non-male factor infertility and advanced maternal age.Journal of assisted reproduction and genetics · 2021Article
- ALWAYS ICSI? A SWOT analysis.Journal of assisted reproduction and genetics · 2020Review
- Tobacco consumption is associated with slow-growing day-6 blastocysts.F&S reports · 2020Article
- ICSI Does Not Improve Live Birth Rates but Yields Higher Cancellation Rates Than Conventional IVF in Unexplained Infertility.Frontiers in medicine · 2020Article
- ICSI Versus Conventional IVF in Women Aged 40 Years or More and Unexplained Infertility: A Retrospective Evaluation of 685 Cycles with Propensity Score Model.Journal of clinical medicine · 2019Article
- ICSI does not offer any benefit over conventional IVF across different ovarian response categories in non-male factor infertility: a European multicenter analysis.Journal of assisted reproduction and genetics · 2019Article
- Dielectrophoretic Microfluidic Device for in Vitro Fertilization.Micromachines · 2018Article
- Role of ICSI in Non-male Factor Cycles as the Number of Oocytes Retrieved Decreases from Four to One.Current medical science · 2018Article
- Is there a reason to perform ICSI in the absence of male factor? Lessons from the Latin American Registry of ART.Human reproduction open · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo determine if patients with a low response to controlled ovarian hyperstimulation during IVF benefit from intracytoplasmic sperm injection (ICSI)
methodsRetrospective analysis of 350 IVF cycles in which four or fewer oocytes were retrieved. Severe male factor cases were excluded from analysis. Conventional insemination (CI) and ICSI were compared, with primary outcome measures of fertilization rate, implantation rate, clinical pregnancy rate per embryo transfer, and pregnancy loss rate. RESULT(S): Fertilization rates per oocyte retrieved for CI and ICSI were comparable (51.5% vs. 51.8%). Parallel implantation rates (22% vs. 25%), clinical pregnancy rates (32.8% vs. 33.3%), and loss rates (26.7% vs. 39.5%) were also noted. No difference in cancelled cycles was reported. CONCLUSION(S): Our results demonstrate that in the presence of normal semen parameters, low egg number is not an indication to perform ICSI.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.