ArticleEuropean archives of psychiatry and clinical neuroscience2012
Subjective emotional over-arousal to neutral social scenes in paranoid schizophrenia.
Article in European archives of psychiatry and clinical neuroscience, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 49 citations in OpenAlex.
- Looking at the other side of the coin: a meta-analysis of self-reported emotional arousal in people with schizophrenia.Schizophrenia research · 2012Pooled it
- Pooled it
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- Self-other boundary under social threat in schizophrenia.Schizophrenia research · 2024Article
- Psychotic Arousal and the Psychopathology of Acute Schizophrenia: An Exploratory Study of the Experiential Emotional State in Acute Psychosis.Journal of clinical medicine · 2024Article
- The Interplay of Oxytocin and Attachment in Schizophrenic Patients: An fMRI Study.Brain sciences · 2023Article
- Neural Circuitry of Salience and Reward Processing in Psychosis.Biological psychiatry global open science · 2023Review
- Perspectives before incremental trans-disciplinary cross-validation of clinical self-evaluation tools and functional MRI in psychiatry: 10 years later.Frontiers in psychiatry · 2022Article
- Altered Peripersonal Space and the Bodily Self in Schizophrenia: A Virtual Reality Study.Schizophrenia bulletin · 2021Article
- Paranoia, sensitization and social inference: findings from two large-scale, multi-round behavioural experiments.Royal Society open science · 2020Article
- The relationships among aberrant salience, reward motivation, and reward sensitivity.International journal of methods in psychiatric research · 2018Article
- Brain responses to different types of salience in antipsychotic naïve first episode psychosis: An fMRI study.Translational psychiatry · 2018Article
- New aspects of the vulnerability stress model in general, its relevance in schizophrenic psychoses and the place of antipsychotics.European archives of psychiatry and clinical neuroscience · 2017Article
- Neural correlates of aberrant emotional salience predict psychotic symptoms and global functioning in high-risk and first-episode psychosis.Social cognitive and affective neuroscience · 2015Article
- The relation between schizotypy and early attention to rejecting interactions: The influence of neuroticism.The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry · 2015Article
- Dorsal raphe neuroinflammation promotes dramatic behavioral stress dysregulation.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2014Article
- Body actions change the appearance of facial expressions.PloS one · 2014Article
- A negative emotional and economic judgment bias in major depression.European archives of psychiatry and clinical neuroscience · 2013Article
- Emotional status: diagnosis and treatment for severe psychiatric disorders.European archives of psychiatry and clinical neuroscience · 2012Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
From the clinical practice and some experimental studies, it is apparent that paranoid schizophrenia patients tend to assign emotional salience to neutral social stimuli. This aberrant cognitive bias has been conceptualized to result from increased emotional arousal, but direct empirical data are scarce. The aim of the present study was to quantify the subjective emotional arousal (SEA) evoked by emotionally non-salient (neutral) compared to emotionally salient (negative) social stimuli in schizophrenia patients and healthy controls. Thirty male inpatients with paranoid schizophrenia psychosis and 30 demographically matched healthy controls rated their level of SEA in response to neutral and negative social scenes from the International Affective Picture System and the Munich Affective Picture System. Schizophrenia patients compared to healthy controls had an increased overall SEA level. This relatively higher SEA was evoked only by the neutral but not by the negative social scenes. To our knowledge, the present study is the first designed to directly demonstrate subjective emotional over-arousal to neutral social scenes in paranoid schizophrenia. This finding might explain previous clinical and experimental data and could be viewed as the missing link between the primary neurobiological and secondary psychological mechanisms of paranoid psychotic-symptom formation. Furthermore, despite being very short and easy to perform, the task we used appeared to be sensitive enough to reveal emotional dysregulation, in terms of emotional disinhibition/hyperactivation in paranoid schizophrenia patients. Thus, it could have further research and clinical applications, including as a neurobehavioral probe for imaging studies.
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