ArticleBiomicrofluidics2011
Curvature-induced dielectrophoresis for continuous separation of particles by charge in spiral microchannels.
Article in Biomicrofluidics, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 71 citations in OpenAlex.
- Microfluidic-based electrically driven particle manipulation techniques for biomedical applications.RSC advances · 2025Review
- pH Gradients in Spatially Non-Uniform AC Electric Fields around the Charging Frequency; A Study of Two Different Geometries and Electrode Passivation.Micromachines · 2023Article
- Dielectrophoretic separation of blood cells.Biomedical microdevices · 2022Review
- Purification of pluripotent embryonic stem cells using dielectrophoresis and a flow control system.Engineering in life sciences · 2022Article
- The latest advances on nonlinear insulator-based electrokinetic microsystems under direct current and low-frequency alternating current fields: a review.Analytical and bioanalytical chemistry · 2022Review
- Particle trapping in electrically driven insulator-based microfluidics: Dielectrophoresis and induced-charge electrokinetics.Electrophoresis · 2021Review
- Insulator Based Dielectrophoresis: Micro, Nano, and Molecular Scale Biological Applications.Sensors (Basel, Switzerland) · 2020Review
- Continuous ES/Feeder Cell-Sorting Device Using Dielectrophoresis and Controlled Fluid Flow.Micromachines · 2020Article
- Analytical Guidelines for Designing Curvature-Induced Dielectrophoretic Particle Manipulation Systems.Micromachines · 2020Article
- Material-selective separation of mixed microparticles via insulator-based dielectrophoresis.Biomicrofluidics · 2019Article
- Three-Dimensional Reservoir-Based Dielectrophoresis (rDEP) for Enhanced Particle Enrichment.Micromachines · 2018Article
- Ripple structure-generated hybrid electrokinetics for on-chip mixing and separating of functionalized beads.Biomicrofluidics · 2014Article
- Joule heating effects on particle immobilization in insulator-based dielectrophoretic devices.Electrophoresis · 2014Article
- Microfluidic electrical sorting of particles based on shape in a spiral microchannel.Biomicrofluidics · 2014Article
- Off-chip passivated-electrode, insulator-based dielectrophoresis (OπDEP).Analytical and bioanalytical chemistry · 2013Article
- Hydrodynamic mechanisms of cell and particle trapping in microfluidics.Biomicrofluidics · 2013Review
- High-throughput particle manipulation by hydrodynamic, electrokinetic, and dielectrophoretic effects in an integrated microfluidic chip.Biomicrofluidics · 2013Article
- Microfluidic separation of live and dead yeast cells using reservoir-based dielectrophoresis.Biomicrofluidics · 2012Article
- Three-dimensional cellular focusing utilizing a combination of insulator-based and metallic dielectrophoresis.Biomicrofluidics · 2011Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The separation of particles from a heterogeneous mixture is critical in chemical and biological analyses. Many methods have been developed to separate particles in microfluidic devices. However, the majority of these separations have been limited to be size based and binary. We demonstrate herein a continuous dc electric field driven separation of carboxyl-coated and noncoated 10 μm polystyrene beads by charge in a double-spiral microchannel. This method exploits the inherent electric field gradients formed within the channel turns to manipulate particles by dielectrophoresis and is thus termed curvature-induced dielectrophoresis. The spiral microchannel is also demonstrated to continuously sort noncoated 5 μm beads, noncoated 10 μm beads, and carboxyl-coated 10 μm beads into different collecting wells by charge and size simultaneously. The observed particle separation processes in different situations are all predicted with reasonable agreements by a numerical model. This curvature-induced dielectrophoresis technique eliminates the in-channel microelectrodes and obstacles that are required in traditional electrode- and insulator-based dielectrophoresis devices. It may potentially be used to separate multiple particle targets by intrinsic properties for lab-on-a-chip applications.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.