Evidence map›Paper›PMID 21791277›Full record

ArticleNeuron2011

Noradrenaline enhances signal-to-noise ratio of inhibitory inputs in the dorsal cochlear nucleus.

Shaul Hestrin

Open access · bronzeAbstract readComment
In one paragraph

Article in Neuron, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Shaul HestrinDepartment of Comparative Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA. shaul.hestrin@stanford.edu
Stanford University · US

Funding

Synaptic Action in the Visual CortexR01EY012114 · NEI · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI HESTRIN, SHAUL · 1998 to 2013
$4.2M
NEI NIH HHS R01 EY012114
6 · The paper itself

Abstract

What are the mechanisms that enhance the response to behaviorally relevant external stimuli? In this issue of Neuron, Kuo and Trussell show that in the dorsal cochlear nucleus, noradrenaline functions to simultaneously reduce spontaneous inhibitory inputs while increasing evoked inhibition.

Identifiers

PMID21791277
PMCPMC3150479
OpenAlexW1971881260

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.