ArticleJournal of occupational medicine and toxicology (London, England)2011
Lung function in asbestos-exposed workers, a systematic review and meta-analysis.
Article in Journal of occupational medicine and toxicology (London, England), 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- A systematic review of the association between pleural plaques and changes in lung function.Occupational and environmental medicine · 2015Pooled it
- Chronic Obstructive Pulmonary Disease: Lifestyle Impact.International journal of preventive medicine · 2024Review
- Non-Malignant Respiratory Illnesses in Association with Occupational Exposure to Asbestos and Other Insulating Materials: Findings from the Alberta Insulator Cohort.International journal of environmental research and public health · 2020Article
- Relations between vital capacity, CO diffusion capacity and computed tomographic findings of former asbestos-exposed patients: a cross-sectional study.Journal of occupational medicine and toxicology (London, England) · 2020Article
- Global DNA hypomethylation has no impact on lung function or serum inflammatory and fibrosis cytokines in asbestos-exposed population.International archives of occupational and environmental health · 2017Article
- Symptoms and lung function decline in a middle-aged cohort of males and females in Australia.International journal of chronic obstructive pulmonary disease · 2016Article
- Role of chest computed tomography in prevention of occupational respiratory disease: review of recent literature.Seminars in respiratory and critical care medicine · 2015Review
- Observational
- Lung Function Profiles among Individuals with Nonmalignant Asbestos-related Disorders.Safety and health at work · 2014Article
- Expression of VPAC1 in a murine model of allergic asthma.Journal of occupational medicine and toxicology (London, England) · 2013Article
- Descriptive analysis of the respiratory health status of persons exposed to Libby amphibole asbestos.BMJ open · 2012Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA continuing controversy exists about whether, asbestos exposure is associated with significant lung function impairments when major radiological abnormalities are lacking. We conducted a systematic review and meta-analysis in order to assess whether asbestos exposure is related to impairment of lung function parameters independently of the radiological findings.
methodsMEDLINE was searched from its inception up to April 2010. We included studies that assessed lung function parameters in asbestos exposed workers and stratified subjects according to radiological findings. Estimates of VC, FEV1 and FEV1/VC with their dispersion measures were extracted and pooled.
resultsOur meta-analysis with data from 9,921 workers exposed to asbestos demonstrates a statistically significant reduction in VC, FEV1 and FEV1/VC, even in those workers without radiological changes. Less severe lung function impairments are detected if the diagnoses are based on (high resolution) computed tomography rather than the less sensitive X-ray images. The degree of lung function impairment was partly related to the proportion of smokers included in the studies.
conclusionsAsbestos exposure is related to restrictive and obstructive lung function impairment. Even in the absence of radiological evidence of parenchymal or pleural diseases there is a trend for functional impairment.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.