Evidence map›Paper›PMID 21790957›Full record

ArticleBJOG : an international journal of obstetrics and gynaecology2011

Post-traumatic stress disorder, child abuse history, birthweight and gestational age: a prospective cohort study.

J S Seng, L K Low, M Sperlich, D L Ronis, I Liberzon

Open access · bronzeAbstract read
In one paragraph

Article in BJOG : an international journal of obstetrics and gynaecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 77 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
77citing papers in PubMed, 4 pooled it
11.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

77 citing papers in PubMed, 4 syntheses or guidelines pooled it, 157 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. The impact of military sexual trauma and warfare exposure on women veterans' perinatal outcomes.Psychological trauma : theory, research, practice and policy · 2022
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article

17 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

J S SengInstitute for Research on Women and Gender, School of Medicine, University of Michigan, Ann Arbor, MI, USA. jseng@umich.edu
L K Low
M Sperlich
D L Ronis
I Liberzon
University of Michigan–Ann Arbor · USInstitute for Women's Policy Research · USVA Ann Arbor Healthcare System · USWayne State University · US

Funding

PSYCHOBIOLOGY OF PTSD &ADVERSE OUTCOMES OF CHILDBEARINGR01NR008767 · NINR · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SENG, JULIA S · 2005 to 2008
$2.1M
NINR NIH HHS NR008767NINR NIH HHS R01 NR008767
6 · The paper itself

Abstract

objectiveTo determine the extent to which prenatal post-traumatic stress disorder (PTSD) is associated with lower birthweight and shorter gestation, and to explore the effects of childhood maltreatment as the antecedent trauma exposure.

designProspective three-cohort study.

settingAnn Arbor and Detroit, Michigan, United States. SAMPLE: In all, 839 diverse nulliparas in PTSD-positive (n = 255), trauma-exposed, resilient (n = 307) and non-exposed to trauma (n = 277) cohorts.

methodsStandardised telephone interview before 28 weeks of gestation to ascertain trauma history, PTSD, depression, substance use, mental health treatment history and sociodemographics, with chart abstraction to obtain chronic condition history, antepartum complications and prenatal care data, as well as outcomes.

main outcome measuresInfant birthweight and gestational age per delivery record.

resultsInfants born to women with PTSD during pregnancy had a mean birthweight 283 g less than infants of trauma-exposed, resilient women and 221 g less than infants of non-exposed women (F(3,835) = 5.4, P = 0.001). PTSD was also associated with shorter gestation in multivariate models that took childhood abuse history into account. Stratified models indicated that PTSD subsequent to child abuse trauma exposure was most strongly associated with adverse outcomes. PTSD was a stronger predictor than African American race of shorter gestation and a nearly equal predictor of birthweight. Prenatal care was not associated with better outcomes among women abused in childhood.

conclusionsAbuse-related PTSD may be an additional or alternative explanation for adverse perinatal outcomes associated with low socio-economic status and African American race in the USA. Biological and interventions research is warranted along with replication studies in other nations.

Indexed as

Birth WeightGestational AgeAdolescentAdultAdult Survivors of Child AbuseFemaleHumansLinear ModelsPregnancyPregnancy OutcomeProspective StudiesSpouse AbuseStress Disorders, Post-TraumaticYoung Adult

Identifiers

PMID21790957
PMCPMC3171570
OpenAlexW2137378820

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.