Evidence map›Paper›PMID 21790955›Full record

SynthesisBJOG : an international journal of obstetrics and gynaecology2011

Shift work and pregnancy outcomes: a systematic review with meta-analysis of currently available epidemiological studies.

M Bonzini, K T Palmer, D Coggon, M Carugno, A Cromi, M M Ferrario

Abstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in BJOG : an international journal of obstetrics and gynaecology, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 61 papers, 9 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
61citing papers in PubMed, 9 pooled it
15.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

61 citing papers in PubMed, 9 syntheses or guidelines pooled it, 153 citations in OpenAlex.

  1. Pooled it
  2. Occupational Risk Factors and Hypertensive Disorders in Pregnancy: A Systematic Review.International journal of environmental research and public health · 2021
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Shift work, long working hours and preterm birth: a systematic review and meta-analysis.International archives of occupational and environmental health · 2014
    Pooled it
  6. Pooled it
  7. Pooled it
  8. Pregnancy: occupational aspects of management: concise guidance.Clinical medicine (London, England) · 2013
    Pooled it
  9. Pooled it
  10. Review
  11. Review
  12. Circadian Regulation of Lipid Metabolism during Pregnancy.International journal of molecular sciences · 2024
    Review
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Review
  20. Greater Risk of Pregnancy Complications for Female Surgeons: A Cross-Sectional Electronic Survey.International journal of environmental research and public health · 2022
    Article

1 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

M BonziniEpidemiology and Preventive Medicine Research Centre, Department of Experimental Medicine, University of Insubria, Varese, Italy. matteo.bonzini@uninsubria.it
K T Palmer
D Coggon
M Carugno
A Cromi
M M Ferrario
MRC Lifecourse Epidemiology Unit · GBOspedale di Circolo e Fondazione Macchi · ITUniversity of Insubria · ITUniversity of Milan · IT

Funding

Medical Research Council MC_UP_A620_1018
6 · The paper itself

Abstract

backgroundVarying work schedules are suspected of increasing risks to pregnant women and to fetal wellbeing. In particular, maternal hormonal disturbance arising from sleep deprivation or circadian rhythm disruption might impair fetal growth or lead to complications of pregnancy. Two independent meta-analyses (from 2000 to 2007) reported a small adverse effect of shift work on the risk of preterm delivery (PTD). However, these reviews were based on few high-quality studies.

objectivesTo provide an updated review of the associations of shift work with PTD, low birthweight (LBW), small-for-gestational-age (SGA) infants and pre-eclampsia. SEARCH STRATEGY AND SELECTION CRITERIA: We conducted a systematic search of MEDLINE using combinations of keywords and MeSH terms. DATA COLLECTION AND ANALYSIS: For each relevant paper we abstracted standard details, used to summarise design features and rate methodological quality. We calculated pooled estimates of relative risk (RR) in random-effect meta-analyses. MAIN

resultsWe retrieved 23 relevant studies. The pooled estimate of RR for PTD was 1.16 (95% CI 1.00-1.33, 16 studies), but when five reports of poorer methodological quality were excluded, the estimated RR decreased to 1.03 (95% CI 0.93-1.14). We also observed increased RRs for LBW (RR 1.27, 95% CI 0.93-1.74) and for SGA (RR 1.12, 95% CI 1.03-1.22), which varied little by study quality. Little evidence was found on pre-eclampsia.

conclusionsThese findings suggest that overall, any risk of PTD, LBW, or SGA arising from shift work in pregnancy is small.

Indexed as

Infant, Low Birth WeightInfant, Small for Gestational AgePregnancy OutcomeWork Schedule ToleranceFemaleHumansInfant, NewbornPre-EclampsiaPregnancyPremature BirthRiskRisk Factors

Identifiers

PMID21790955
PMCPMC3388382
OpenAlexW2130014503

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.