Evidence map›Paper›PMID 21790112›Full record

ReviewOphthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye2011

The role of spectral-domain OCT in the diagnosis and management of neovascular age-related macular degeneration.

Caio V Regatieri, Lauren Branchini, Jay S Duker

Abstract readReview
In one paragraph

Review in Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye, 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Choroidal imaging biomarkers as predictors of conversion to exudative age-related macular degeneration.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2025
    Article
  7. Article
  8. Central posterior hyaloid fibrosis: evolution and outcomes.International journal of retina and vitreous · 2023
    Article
  9. Review
  10. Article
  11. Observational
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Deep learning-based detection and classification of geographic atrophy using a deep convolutional neural network classifier.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Caio V RegatieriNew England Eye Center, Tufts Medical Center, 800 Washington Street, Boston, MA 02111, USA.
Lauren Branchini
Jay S Duker

Funding

Novel Glaucoma Diagnostics for Structure and Function - Renewal - 1R01EY013178 · NEI · WILLS EYE HEALTH SYSTEM · PI Joel S Schuman · 2000 to 2026
$17.5M
Advanced Imaging for GlaucomaR01EY013516 · NEI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HUANG, DAVID · 2003 to 2012
$15.9M
Novel Optical Diagnostics with Optical Coherence TomographyR01EY011289 · NEI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI JAMES G FUJIMOTO · 1995 to 2026
$9.5M
NEI NIH HHS R01 EY011289NEI NIH HHS R01 EY013178NEI NIH HHS R01 EY013516NEI NIH HHS R01-EY013516-07NEI NIH HHS R01-EY11289-23NEI NIH HHS R01-EY13178-07
6 · The paper itself

Abstract

Spectral-domain optical coherence tomography (SD-OCT) has emerged as the ancillary examination of choice to assist the diagnosis and management of neovascular age-related macular degeneration (AMD). SD-OCT provides more detailed images of intraretinal, subretinal, and subretinal pigment epithelium fluid when compared to time-domain technology, leading to higher and earlier detection rates of neovascular AMD activity. Improvements in image analysis and acquisition speed make it important for decision-making in the diagnosis and treatment of this disease. However, this new technology needs to be validated for its role in the improvement of visual outcomes in the context of anti-angiogenic therapy.

Indexed as

Diagnostic Techniques, OphthalmologicalTomography, Optical CoherenceHumansVisual AcuityWet Macular Degeneration

Identifiers

PMID21790112
PMCPMC3375172

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.