Evidence map›Paper›PMID 21789740›Full record

ArticleStrahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al]2011

Monte Carlo simulations applied to conjunctival lymphoma radiotherapy treatment.

Lorenzo Brualla, Ricardo Palanco-Zamora, Klaus-Peter Steuhl, Norbert Bornfeld, Wolfgang Sauerwein

Abstract read
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In one paragraph

Article in Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al], 2011. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 16 citations in OpenAlex.

  1. Article
  2. Article
  3. Monte Carlo systems used for treatment planning and dose verification.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2017
    Review
  4. Article
  5. PRIMO: a graphical environment for the Monte Carlo simulation of Varian and Elekta linacs.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013
    Article
  6. Accurate estimation of dose distributions inside an eye irradiated with 106Ru plaques.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2013
    Article
  7. Clinical relevance of different dose calculation strategies for mediastinal IMRT in Hodgkin's disease.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2012
    Article
  8. Review
  9. Comparison between Acuros XB and Brainlab Monte Carlo algorithms for photon dose calculation.Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] · 2012
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lorenzo BruallaNCTeam, Strahlenklinik, Universitätsklinikum Essen, Essen, Germany. lorenzo.brualla@uni-duisburg-essen.de
Ricardo Palanco-Zamora
Klaus-Peter Steuhl
Norbert Bornfeld
Wolfgang Sauerwein
Essen University Hospital · DEKarolinska University Hospital · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionSmall radiation fields are increasingly applied in clinical routine. In particular, they are necessary for the treatment of eye tumors. However, available treatment planning systems do not calculate the absorbed dose with the desired accuracy in the presence of small fields. Absorbed dose estimations obtained with Monte Carlo methods have the required accuracy for clinical applications, but the exceedingly long computation times associated with them hinder their routine use. In this article, a code for automatic Monte Carlo simulation of linacs and an application in the treatment of conjunctival lymphoma are presented.

methodsSimulations of clinical linear accelerators were performed with the general-purpose radiation transport Monte Carlo code penelope. Accelerator geometry files, in electron mode, were generated with the program AutolinaC.

resultsThe Monte Carlo simulation of an annular electron 6 MeV field used for the treatment of the conjunctival lymphoma yielded absorbed dose results statistically compatible with experimental measurements. In this simulation, 2% standard statistical uncertainty was reached in the same time employed by a hybrid Monte Carlo commercial code (eMC); however, eMC showed discrepancies of up to 7% on the absorbed dose with respect to experimental data. Results obtained with the analytic algorithm Pencil Beam Convolution differed from experimental data by 10% for this case.

conclusionOwing to the systematic application of variance-reduction techniques, it is possible to accurately estimate the absorbed dose in patient images, using Monte Carlo methods, in times within clinical routine requirements. The program AutolinaC allows systematic use of these variance-reduction techniques within the code penelope.

Indexed as

Computer SimulationMathematical ComputingMonte Carlo MethodAlgorithmsConjunctival NeoplasmsEquipment DesignHumansImaging, Three-DimensionalLymphomaPhantoms, ImagingSoftwareSurgery, Computer-AssistedTomography, X-Ray Computed

Identifiers

PMID21789740
OpenAlexW12050735

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.